Peritoneal fluid interleukin-6 in women with chronic pelvic pain

Andrea J. Rapkin, A Rapkin, Rapkin A, Melinda Morgan, M Morgan, Morgan M, Bonpane C, Colleen M. Bonpane, C Bonpane, O Martinez-Maza, Otoniel Martı́nez-Maza, Martinez-Maza O
Fertility and sterility · 2000 · vol. 74(2) , pp. 325–328 · doi:10.1016/s0015-0282(00)00653-1 · PMID:10927052 · W2077868127
article OA: closed CC0 ⤵ 27 in-corpus citations
🔓 Open OA copy View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-09 ⓘ

This study investigated peritoneal fluid interleukin-6 levels in women diagnosed with chronic pelvic pain.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

ObjectiveTo determine the relationship between peritoneal fluid concentrations of interleukin-6 (IL-6) and chronic pelvic pain symptomatology in women with adhesions, endometriosis, or no obvious intraperitoneal pathology.DesignClinical research study.SettingHealthy volunteers in an academic research environment.Patient(s)Reproductive-aged women undergoing laparoscopy for the diagnosis of pelvic pain, infertility, or sterilization were selected.Intervention(s)Peritoneal fluid was collected at the time of the laparoscopy and later assayed for IL-6. Subjects completed a pelvic pain questionnaire, and operative reports were used to obtain the underlying diagnosis.Main outcome measure(s)Interleukin-6 concentrations.Result(s)No correlation between the presence or absence of pelvic pain, findings of adhesions or endometriosis, and the concentration of peritoneal fluid IL-6 was observed.Conclusion(s)The cytokine IL-6 does not seem to play a role in the genesis of chronic pelvic pain in women with adhesions or endometriosis.

My notes (saved in your browser only)

Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Ascitic Fluid Interleukin-6 Pelvic Pain Ascitic Fluid Endometriosis Endometriosis Endometriosis Female Humans Interleukin-6 Interleukin-6 Laparoscopy Ovarian Diseases Ovarian Diseases Ovarian Diseases Ovarian Diseases Pelvic Pain Pelvic Pain Predictive Value of Tests Reference Values

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (22)

Cited by (27)

Source provenance

europepmc
last seen: 2026-10-08T06:18:23.926119+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:13:36.046895+00:00
unpaywall
last seen: 2026-09-17T06:32:46.214484+00:00
License: CC0 · commercial use OK