Local application of danazol-loaded hyaluronic acid hydrogel to endometriosis in a rat model

Kazuhito Nomura, Koichi Murakami, Makio Shozu, Tsuyoshi Nakama, Nobuhiko Yui, Masaki Inoue
Fertility and sterility · 2006 · vol. 85 , pp. 1157–1167 · doi:10.1016/j.fertnstert.2005.08.057 · PMID:16616088 · W1970921466
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This study investigated the effects of locally applying a danazol-loaded hyaluronic acid hydrogel to endometriosis in a rat model.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-11 · read from full text ⓘ

This doctoral study investigated local treatment of endometriosis in a rat model using a danazol-loaded hyaluronic acid hydrogel. The authors assessed the effects of administering the hydrogel locally, aiming to deliver danazol to endometriotic lesions rather than using systemic exposure. The key finding reported is the therapeutic impact of this local danazol/hyaluronic acid gel approach in the endometriosis rat model, consistent with the rationale for localized hormone delivery. The main caveat is that the provided text is only bibliographic metadata/abstract information without methodological or quantitative outcome details. This paper is centrally about endometriosis — it evaluates local danazol-loaded hyaluronic acid hydrogel therapy in a rat model of endometriosis.

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WEKO3 アイテム Local application of danazol-loaded hyaluronic acid hydrogel to endometriosis in a rat model http://hdl.handle.net/2297/14721 http://hdl.handle.net/2297/147211ef20e84-aafa-44e5-9743-f8d5847be93f | 名前 / ファイル | ライセンス | アクション | |---|---|---| | nomura-2006-43.pdf (106.6 kB) | | | アイテムタイプ | その他 / Others(1) | ||||| |---|---|---|---|---|---|---| | 公開日 | 2017-10-05 | ||||| | タイトル | |||||| | タイトル | Local application of danazol-loaded hyaluronic acid hydrogel to endometriosis in a rat model | ||||| | 言語 | |||||| | 言語 | eng | ||||| | 資源タイプ | |||||| | 資源タイプ識別子 | http://purl.org/coar/resource_type/c_1843 | ||||| | 資源タイプ | other | ||||| | その他のタイトル | |||||| | その他のタイトル | ラット子宮内膜症モデルに対するダナゾール含有ヒアルロン酸ゲルによる局所療法 | ||||| | 著者 | Nomura, Kazuhito × Nomura, Kazuhito | ||||| | 著者別名 | |||||| | 値 | 野村, 一人 | ||||| | 書誌情報 | 博士学位論文要旨 論文内容の要旨および論文審査結果の要旨／金沢大学大学院医学研究科 巻 平成18年7月, p. 43-43, 発行日 2006-07-01 | ||||| | PMID | |||||| | 関連タイプ | isIdenticalTo | ||||| | 識別子タイプ | PMID | ||||| | 関連識別子 | 16616088 | ||||| | その他の識別子 | |||||| | 内容記述タイプ | Other | ||||| | 内容記述 | 000008383265 | ||||| | 出版者 | |||||| | 出版者 | 金沢大学 | ||||| | 内容記述 | |||||| | 内容記述タイプ | Other | ||||| | 内容記述 | 取得学位 : 博士（医学）, 学位授与番号 : 医博甲第1755号 , 学位授与年月日 : 平成18年3月22日, 学位授与大学 : 金沢大学 | ||||| | 著者版フラグ | |||||| | 出版タイプ | VoR | ||||| | 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |

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Condition tags

endometriosis

MeSH descriptors

Danazol Danazol Disease Models, Animal Drug Delivery Systems Endometriosis Endometriosis Hyaluronic Acid Animals Danazol Drug Carriers Drug Carriers Drug Carriers Drug Delivery Systems Endometriosis Endometrium Endometrium Endometrium Estrogen Antagonists Estrogen Antagonists Female

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (43)

Cited by (7)

Source provenance

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