Makio Shozu

OBJECTIVE(S): To assess the prevalence of chronic endometritis (CE) in patients with infertility and hydrosalpinx or peritubal adhesions and to examine the effects of laparoscopic surgical correction (LSC) on CE and pregnancy rates post in …

When transplacental therapy is conducted, the maternal serum concentrations of digoxin and flecainide may fluctuate throughout third trimester. Therefore, TDM may be effective in improving the efficacy and safety of treatment.

•A cul-de-sac endometrioid carcinoma adjacent to extraovarian endometriosis was identified during remission of endometrial cancer.•The origin of the cul-de-sac tumor was malignant transformation of deep infiltrating endometriosis.•Endometri…

BackgroundTo achieve optimal cytoreduction for advanced-stage ovarian cancer, modified posterior exenteration is the most frequently performed bowel surgery. We assessed the extents of tumor spreading in the rectosigmoid wall and pelvic sid…

AIMS: The carcinogenesis of ovarian clear cell carcinoma (CCC) has been hypothesized to comprise two different pathways: an adenofibroma-carcinoma sequence and an endometriosis-carcinoma sequence. However, the difference in the genetic basi…

Keishibukuryogan (KBG; Guizhi-Fuling-Wan in Chinese) is one of the Kampo (Japanese traditional) medicines used to treat patients with climacteric syndrome. KBG can be used by patients who cannot undergo hormone replacement therapy due to a …

Cyp19a1Aromatase excess syndrome is characterized by pre- or peripubertal onset of gynecomastia due to estrogen excess because of a gain-of-function mutation in the aromatase gene (CYP19A1). Subchromosomal recombination events including dup…

Risk-reducing salpingo-oophorectomy for reducing future cancer risk in women with hereditary breast and ovarian cancer syndrome is rarely performed in Japan; therefore, the cancer pre-ventive effect of risk-reducing salpingo-oophorectomy fo…

Copyright information:Taken from "Small primary adenocarcinoma in adenomyosis with nodal metastasis: a case report"http://www.biomedcentral.com/1471-2407/7/103BMC Cancer 2007;7():103-103.Published online 20 Jun 2007PMCID:PMC1913924. Patchy …

Copyright information:Taken from "Small primary adenocarcinoma in adenomyosis with nodal metastasis: a case report"http://www.biomedcentral.com/1471-2407/7/103BMC Cancer 2007;7():103-103.Published online 20 Jun 2007PMCID:PMC1913924. Patchy …

Copyright information:Taken from "Small primary adenocarcinoma in adenomyosis with nodal metastasis: a case report"http://www.biomedcentral.com/1471-2407/7/103BMC Cancer 2007;7():103-103.Published online 20 Jun 2007PMCID:PMC1913924. Aromata…

Copyright information:Taken from "Small primary adenocarcinoma in adenomyosis with nodal metastasis: a case report"http://www.biomedcentral.com/1471-2407/7/103BMC Cancer 2007;7():103-103.Published online 20 Jun 2007PMCID:PMC1913924. Aromata…

BACKGROUND: Malignant transformation of adenomyosis is a very rare event. Only about 30 cases of this occurrence have been documented till now. CASE PRESENTATION: The patient was a 57-year-old woman with a slightly enlarged uterus, who unde…

Molecular abnormalities in the epithelial cells of endometriosis and their relevance to carcinogenesis of the ovary have been well studied. On the other hand, the differences of proinflammatory microenvironments between endometriosis and ov…

OBJECTIVE: To evaluate the inhibitory effect of danazol on estrogen (E) production in endometriosis. DESIGN: Prospective randomized study. SETTING: Academic research unit of the department of obstetrics and gynecology in a university hosp…

ObjectiveTo evaluate the efficacy of a drug delivery system composed of danazol-loaded hyaluronic acid for local application to endometriosis.DesignProspective, randomized study.SettingAcademic research unit of the department of obstetrics …

Endometriosis is an estrogen-dependent disease of women of reproductive age. Recent studies demonstrate that endometriosis per se express high levels of estrogen synthetase (aromatase P450). The resulting estrogen synthesized in situ may pl…