Activation of mammalian target of rapamycin in postmenopausal ovarian endometriosis

Tatsuo Yagyu; Yasushi Tsuji; Shoji Haruta; Takashi Kitanaka; Yuki YAMADA; Ryuji Kawaguchi; Seiji Kanayama; Yasuhito Tanase; Noriyuki Kurita; Hiroshi Kobayashi

doi:10.1136/ijgc-00009577-200607000-00008

Activation of mammalian target of rapamycin in postmenopausal ovarian endometriosis

Tatsuo Yagyu, Yasushi Tsuji, Shoji Haruta, Takashi Kitanaka, Yuki YAMADA, Ryuji Kawaguchi, Seiji Kanayama, Yasuhito Tanase, Noriyuki Kurita, Hiroshi Kobayashi

In: International Journal of Gynecological Cancer · 2006 · vol. 16(4) , pp. 1545–1551 · doi:10.1136/ijgc-00009577-200607000-00008 · W4399166793

OA: closed CC0 ⤵ 7 in-corpus citations

🔓 Open OA copy View on OpenAlex View at publisher

⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

This study investigated the role of mammalian target of rapamycin activation in postmenopausal ovarian endometriosis.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

My notes (saved in your browser only)

Condition tags

endometriosis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (37)

Allelic loss studies do not provide evidence for the "endometriosis-as-tumor" theory via openalex
Apoptosis in human endometrium and endometriosis via openalex
Common genetic changes between endometriosis and ovarian cancer via openalex
Endometriosis and ovarian cancer: thoughts on shared pathophysiology via openalex
Endometriosis and the neoplastic process via openalex
Endometriotic cells are resistant to interferon-gamma-induced cell growth inhibition and apoptosis: a possible mechanism involved in the pathogenesis of endometriosis via openalex
Expression of apoptosis-related proteins in endometriomas and benign and malignant ovarian tumours via openalex
Increased prevalence of p53 overexpression from typical endometriosis to atypical endometriosis and ovarian cancer associated with endometriosis via openalex
K-ras mutation may promote carcinogenesis of endometriosis leading to ovarian clear cell carcinoma via openalex
Malignant transformation of endometriosis and genetic alterations of K-ras and microsatellite instability via openalex
Microsatellite DNA assays reveal an allelic imbalance in p16(Ink4), GALT, p53, and APOA2 loci in patients with endometriosis via openalex
Molecular genetic defects in endometriosis via openalex
Molecular mechanisms and biological plausibility underlying the malignant transformation of endometriosis: a critical analysis via openalex
p53 mutations and overexpression affect prognosis of ovarian endometrioid cancer but not clear cell cancer via openalex
Recent advances in endometriosis with emphasis on pathogenesis, molecular pathology, and neoplastic transformation via openalex
Reduction of apoptosis and proliferation in endometriosis via openalex
Revised American Society for Reproductive Medicine classification of endometriosis: 1996 via openalex
Role of endometriosis in cancer and tumor development via openalex
Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer via openalex
Therapeutic effect of angiostatin gene transfer in a murine model of endometriosis via openalex
Ubiquitin is associated with the survival of ectopic stromal cells in endometriosis via openalex
W6678815053 via openalex
W2042041038 via openalex
W2050084756 via openalex
W2058720172 via openalex
W2095613768 via openalex
W2121117803 via openalex
W2128319359 via openalex
W2133535504 via openalex
W2166562978 via openalex
W2439361580 via openalex
W4313490420 via openalex
W6604024384 via openalex
W6630262600 via openalex
W6638686170 via openalex
W6675287977 via openalex
W1555073840 via openalex

Cited by (7)

Source provenance

openalex: last seen: 2026-06-10T17:14:06.276822+00:00
unpaywall: last seen: 2026-09-17T06:32:46.214484+00:00

License: CC0 · commercial use OK

[1] Allelic loss studies do not provide evidence for the "endometriosis-as-tumor" theory via openalex

[2] Apoptosis in human endometrium and endometriosis via openalex

[3] Common genetic changes between endometriosis and ovarian cancer via openalex

[4] Endometriosis and ovarian cancer: thoughts on shared pathophysiology via openalex

[5] Endometriosis and the neoplastic process via openalex

[6] Endometriotic cells are resistant to interferon-gamma-induced cell growth inhibition and apoptosis: a possible mechanism involved in the pathogenesis of endometriosis via openalex

[7] Expression of apoptosis-related proteins in endometriomas and benign and malignant ovarian tumours via openalex

[8] Increased prevalence of p53 overexpression from typical endometriosis to atypical endometriosis and ovarian cancer associated with endometriosis via openalex

[9] K-ras mutation may promote carcinogenesis of endometriosis leading to ovarian clear cell carcinoma via openalex

[10] Malignant transformation of endometriosis and genetic alterations of K-ras and microsatellite instability via openalex

[11] Microsatellite DNA assays reveal an allelic imbalance in p16(Ink4), GALT, p53, and APOA2 loci in patients with endometriosis via openalex

[12] Molecular genetic defects in endometriosis via openalex

[13] Molecular mechanisms and biological plausibility underlying the malignant transformation of endometriosis: a critical analysis via openalex

[14] p53 mutations and overexpression affect prognosis of ovarian endometrioid cancer but not clear cell cancer via openalex

[15] Recent advances in endometriosis with emphasis on pathogenesis, molecular pathology, and neoplastic transformation via openalex

[16] Reduction of apoptosis and proliferation in endometriosis via openalex

[17] Revised American Society for Reproductive Medicine classification of endometriosis: 1996 via openalex

[18] Role of endometriosis in cancer and tumor development via openalex

[19] Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer via openalex

[20] Therapeutic effect of angiostatin gene transfer in a murine model of endometriosis via openalex

[21] Ubiquitin is associated with the survival of ectopic stromal cells in endometriosis via openalex

[22] W6678815053 via openalex

[23] W2042041038 via openalex

[24] W2050084756 via openalex

[25] W2058720172 via openalex

[26] W2095613768 via openalex

[27] W2121117803 via openalex

[28] W2128319359 via openalex

[29] W2133535504 via openalex

[30] W2166562978 via openalex

[31] W2439361580 via openalex

[32] W4313490420 via openalex

[33] W6604024384 via openalex

[34] W6630262600 via openalex

[35] W6638686170 via openalex

[36] W6675287977 via openalex

[37] W1555073840 via openalex