Pavlovich SV

No ORCID on file · 12 papers in corpus · active 2006-2024

Study types

  • article 8
  • other 1
  • preprint 1

Condition tags

  • endometriosis 10
  • infertility 1
  • endometrioma 1
  • die_deep_infiltrating 1
2024
Analysis of CDO1, PITX2, and CDH13 Gene Methylation in Early Endometrial Cancer for Prediction of Medical Treatment Outcomes.
International journal of molecular sciences ·doi:10.3390/ijms25094892

An observational cohort study of patients diagnosed with endometrial cancer (EC) stage IA G1, or atypical endometrial hyperplasia (AEH), undergoing organ-preserving treatment, was conducted.Objective of the studyTo determine CDO1, PITX2, an…

article 2024
Diagnostic Value of Menstrual Blood Lipidomics in Endometriosis: A Pilot Study
Biomolecules ·doi:10.3390/biom14080899

Endometriosis is a prevalent chronic inflammatory disease characterized by a considerable delay between initial symptoms and diagnosis through surgery. The pressing need for a timely, non-invasive diagnostic solution underscores the focus o…

preprint 2024
Diagnostic Value of Menstrual Blood Lipidomics in Endometriosis: A Pilot Study
·doi:10.20944/preprints202405.1326.v1

Endometriosis is a prevalent chronic inflammatory disease characterized by a considerable delay between initial symptoms and diagnosis through surgery. The pressing need for a timely, non-invasive diagnostic solution underscores the focus o…

article 2023
Potential Significance of Serum Autoantibodies to Endometrial Antigens, α-Enolase and Hormones in Non-Invasive Diagnosis and Pathogenesis of Endometriosis
International journal of molecular sciences ·doi:10.3390/ijms242115578

The objective of the study was to evaluate the profile of serum autoantibodies and their diagnostic and pathogenetic significance in ovarian endometrioma (OEM) and deep infiltrative endometriosis (DIE). The study enrolled 74 patients with e…

article 2022
The Levels of Ghrelin, Glucagon, Visfatin and Glp-1 Are Decreased in the Peritoneal Fluid of Women with Endometriosis along with the Increased Expression of the CD10 Protease by the Macrophages
International journal of molecular sciences ·doi:10.3390/ijms231810361

The aim of this study was to evaluate the levels of ten energy metabolism factors: C-peptide, ghrelin, GIP, GLP-1, glucagon, insulin, leptin, PAI-1 (total), resistin, and visfatin, and to determine the expression of GLP1R receptors, CD10, C…

article 2021
Mesenchymal Stromal Cells Isolated from Ectopic but Not Eutopic Endometrium Display Pronounced Immunomodulatory Activity In Vitro
Biomedicines ·doi:10.3390/biomedicines9101286

A comparative analysis of the cell surface markers and immunological properties of cell cultures originating from normal endometrium and endometrioid heterotopias of women with extragenital endometriosis was carried out. Both types of cell …

article 2021
N-Acyl Dopamines Induce Apoptosis in Endometrial Stromal Cells from Patients with Endometriosis
International journal of molecular sciences ·doi:10.3390/ijms221910648

Endometriosis is characterized by the formation and development of endometrial tissues outside the uterus, based on an imbalance between proliferation and cell death, leading to the uncontrolled growth of ectopic foci. The potential target …

article 2020
Autoimmune markers for non-invasive diagnosis of endometriosis in women
Biomeditsinskaia khimiia ·doi:10.18097/pbmc20206602162

Endometriosis is a common estrogen-dependent chronic disease in women of reproductive age; it is associated with dysregulation of the immune response, local inflammation, and increased formation of autoantibodies. The aim of the study was t…

article 2019
Selective Action of N-Arachidonoyl Dopamine on Viability and Proliferation of Stromal Cells from Eutopic and Ectopic Endometrium
Bulletin of experimental biology and medicine ·doi:10.1007/s10517-019-04456-6

We performed a comparative study of the cytotoxic effect of endocannabinoid N-arachidonoyl dopamine (AA-DA) on cultured stromal cells of ectopic and eutopic endometrium. It was found that AA-DA in the concentration range of 1-20 μM produces…

article 2019
The content of cytokines IL-6, IL-8, TNF-α, IL-4 and the level of expression in macrophages CD86 and CD163 in peritoneal fluid has a reverse correlation with the degree of severity of external genital endometriosis
Biomeditsinskaia khimiia ·doi:10.18097/pbmc20196505432

Concentrations of eight different cytokines and the level of expression of CD86 and CD163 macrophages were studied in peritoneal fluid in women with endometriosis. It was found that the concentration of both inflammatory (IL-6, IL-8, TNF-α)…

2016
Hyaluronic Acid in Vascular and Immune Homeostasis during Normal Pregnancy and Preeclampsia.
Acta naturae ·doi:10.32607/20758251-2016-8-3-59-71

Preeclampsia (PE) is a multisystem pathologic state that clinically manifests itself after the 20th week of pregnancy. It is characterized by high maternal and perinatal morbidity and mortality. According to modern concepts, the impairment …

other 2006
Apoptosis and proliferative activity in endometrium during peritoneal endometriosis
Bulletin of experimental biology and medicine ·doi:10.1007/s10517-006-0128-x

Apoptosis and proliferative activity of the glandular epithelium and endometrial stroma in patients with peritoneal endometriosis and in women of reproductive age without endometriosis were studied at various stages of menstrual cycle. Diff…