Charanjit S. Bambra

OBJECTIVE: To test the hypothesis that a recent corpus luteumn (CL) withoutfresh ovulation stigma (OS) can befound uwth a higher incidence and recurrence in baboons with endometriosis and is associated Lith a reduced egg recovery rate after…

To the best of our knowledge this is the first prospective study in nonhuman primates of proven fertility in the wild, which compares fertility between animals with spontaneous minimal endometriosis and those with a normal pelvis. During 7 …

The histopathology of spontaneous endometriosis was studied on 20 pelvic implants biopsied at laparoscopy in 15 healthy baboons. Endometriosis was confirmed by histopathology in 10 of these animals (66%). Typical (n = 3) and subtle (n = 13)…

BACKGROUND: Serum CA-125 during the mid-follicular phase has been reported to be a clinically useful and reproducible marker in the diagnosis of advanced endometriosis in women. This study was undertaken to document the effect of the menstr…

ObjectiveOur purpose was to test the hypothesis that menstruation and intrapelvic injection of endometrium for the induction of endometriosis affect inflammatory parameters in peritoneal fluid from baboons.Study designIn the first part of t…

ObjectiveTo test the hypothesis that diagnostic laparoscopy can cause pelviperitoneal inflammation.DesignRetrospective analysis of data collected during a prospective controlled study in baboons.SettingAn academic research environment.Anima…

BackgroundThis study was performed to test the hypothesis that endometriosis undergoes regression during pregnancy.MethodsThis study was performed on 11 baboons with histologically proven endometriosis, housed at the Institute of Primate Re…

OBJECTIVE: To determine the incidence of spontaneous endometriosis over a 32-month period in baboons with initially normal pelves. METHODS: In this observational longitudinal study, which was performed at the Institute of Primate Research, …

In women with endometriosis, changes in peripheral blood and peritoneal fluid white blood cell (WBC) populations have been reported, but it is known whether these alterations are casually related to or a consequence of endometriosis. The pu…

This study was done to test the hypothesis that the incidence and recurrence of retrograde menstruation is higher in baboons with spontaneous endometriosis than in those without. A total of 399 laparoscopies was performed on 113 female babo…

ObjectiveTo test the hypothesis that a recent corpus luteum (CL) without fresh ovulation stigma (OS) can be found with a higher incidence and recurrence in baboons with endometriosis and is associated with a reduced egg recovery rate after …

ObjectiveTo test the hypothesis that spontaneous endometriosis is a progressive disease in baboons.Design and settingProspective cohort study, Institute of Primate Research, Nairobi, Kenya.ParticipantsTwelve baboons with histologically prov…

BACKGROUND: It is not known whether stress affects the prevalence of endometriosis in women. Baboons with spontaneous endometriosis may be interesting models to study the human disease. For baboons, living in captivity is a period of chroni…

ObjectivesTo determine if microscopic endometriosis exists in visually normal pelvic peritoneum from baboons with and without endometriosis.DesignObservational histologic study at Institute of Primate Research, Nairobi, Kenya.SubjectsSevent…

This study was performed to test the hypothesis that anti-endometrial, lymphocyte-mediated cytotoxicity and natural killer (NK) activity are reduced in baboons with endometriosis when compared to animals with a normal pelvis. Lymphocyte-med…

ObjectiveThe Sampson hypothesis of retrograde menstruation as a cause of endometriosis was tested by determining the effect of intrapelvic injection of menstrual versus luteal endometrium on the incidence, peritoneal involvement, and stage …

This study was performed to document for the first time peritoneal fluid volumes and steroid hormone levels in baboons with and without endometriosis. A laparoscopy was carried out in 19 female baboons (11 with a normal pelvis and 8 with hi…

The prevalence of spontaneous endometriosis was investigated by laparoscopy in 52 baboons (Papio anubis and Papio cynocephalus) of proven fertility. Clinical endometriosis was diagnosed in 9 (17%) and 4 (8%) baboons with or without a previo…