The effect of pregnancy on endometriosis in baboons (Papio anubis, Papio cynocephalus) *

T M D'Hooghe, Thomas D’Hooghe, D'Hooghe TM, Bambra CS, Charanjit S. Bambra, C S Bambra, I De Jonge, De Jonge I, Lauweryns Jm, J. M. Lauweryns, B M Raeymaekers, Raeymaekers BM, B RAEYMAEKERS, Koninckx PR, Philippe R. Koninckx, P R Koninckx
Archives of gynecology and obstetrics · 1997 · vol. 261(1) , pp. 15–19 · doi:10.1007/s004040050191 · PMID:9451518 · W1964282112
article OA: closed CC0 ⤵ 21 in-corpus citations
Full text JSON View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06+body, 2026-06-08 ⓘ

This study examined endometriosis in 11 baboons, finding no significant change in lesion characteristics or severity during the first or second trimester of pregnancy compared to their nonpregnant state.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-09 · read from full text ⓘ

This study tested the hypothesis that endometriosis regresses during pregnancy by examining 11 baboons with histologically proven endometriosis using paired laparoscopies before pregnancy and during the first (n=6) or second trimester (n=5), with a 5±3 month interval. During each laparoscopy, the investigators recorded number, size, and type of endometriotic implants on a pelvic map and calculated endometriosis score and stage using the revised American Fertility Society (AFS) classification, comparing pregnant versus nonpregnant states with Wilcoxon signed rank tests. They found no significant change in AFS score or stage, nor in the number, size, or type of lesions across gestation. This paper is centrally about endometriosis—specifically, it evaluates whether pregnancy induces regression of endometriosis in baboons.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

BackgroundThis study was performed to test the hypothesis that endometriosis undergoes regression during pregnancy.MethodsThis study was performed on 11 baboons with histologically proven endometriosis, housed at the Institute of Primate Research, Nairobi, Kenya. In each individual baboon paired laparoscopies were performed prior to and during pregnancy (6 during first and 5 during second trimester of gestation) with an interval of 5 +/- 3 months. During each laparoscopy the number, size and type of endometriosis implants were noted in detail on a pelvic map; the endometriosis score and stage were calculated according to the revised American Fertility Society (AFS) classification. In each baboon the observations prior to and during pregnancy were compared and analysed by Wilcoxon signed rank test (two-tailed).ResultsNo significant change was observed in the AFS score or stage of endometriosis, or in the number, size and type of endometriotic lesions in baboons during gestation when compared to the nonpregnant state.ConclusionIn baboons pregnancy had no significant effect on endometriosis during the first or second trimester of gestation.
Full text 1,658 characters · extracted from oa-doi-fallback · click to expand
Abstract. Background: This study was performed to test the hypothesis that endometriosis undergoes regression during pregnancy. Methods: This study was performed on 11 baboons with histologically proven endometriosis, housed at the Institute of Primate Research, Nairobi, Kenya. In each individual baboon paired laparoscopies were performed prior to and during pregnancy (6 during first and 5 during second trimester of gestation) with an interval of 5±3 months. During each laparoscopy the number, size and type of endometriosis implants were noted in detail on a pelvic map; the endometriosis score and stage were calculated according to the revised American Fertility Society (AFS) classification. In each baboon the observations prior to and during pregnancy were compared and analysed by Wilcoxon signed rank test (two-tailed). Results: No significant change was observed in the AFS score or stage of endometriosis, or in the number, size and type of endometriotic lesions in baboons during gestation when compared to the nonpregnant state. Conclusion: In baboons pregnancy had no significant effect on endometriosis during the first or second trimester of gestation. Similar content being viewed by others Author information Authors and Affiliations Additional information Received: 13 December 1996 / Accepted: 21 May 1997 Rights and permissions About this article Cite this article D'Hooghe, T., Bambra, C., De Jonge, I. et al. The effect of pregnancy on endometriosis in baboons (Papio anubis, Papio cynocephalus) * . Arch Gynecol Obstet 261, 15–19 (1997). https://doi.org/10.1007/s004040050191 Issue date: DOI: https://doi.org/10.1007/s004040050191

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriosis

MeSH descriptors

Endometriosis Papio Pregnancy, Animal Pregnancy Complications Animals Biopsy Cricetinae Disease Models, Animal Endometriosis Endometriosis Female Laparoscopy Papio Papio Pelvis Pelvis Pregnancy Pregnancy Complications Pregnancy Complications

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (14)

Cited by (21)

Source provenance

europepmc
last seen: 2026-08-04T06:16:37.499272+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:10:52.568893+00:00
License: CC0 · commercial use OK