Adenomyosis refers to the occurrence of ectopic endometrial glands and the surrounding stroma within the myometrium. A distinction is made between diffuse and focal forms (rare nodular forms and an adenomyoma). Ectopic pregnancy (EUG) occur…
INTRODUCTION: It is suspected that uterine malformations and endometriosis have a high coincidence. Furthermore, it is expected that obstructive uterine malformations are significantly higher affected than non-obstructive malformations. The…
Wir präsentieren den Fall einer 33-jährigen Frau GII / PI, die sich in der 6. Schwangerschaftswoche bei einer vaginalen Blutung vorstellte. Die nächste Vorstellung erfolgte in 7 + 3 SSW aufgrund der wehenartigen Unterbauchschmerzen sowie da…
Optimizing menopausal hormone therapy (MHT) requires an awareness of the benefits and risks associated with the available treatments. This narrative review, which is based on the proceedings of an Advisory Board meeting and supplemented by …
Objective: Endometriosis affects up to 10% of women of reproductive age, and the main goal of treatment is to relieve symptoms. Progestins have been the mainstay of endometriosis suppression, of which dienogest has become an important optio…
In the original publication of the article, the word laparotomy has been presented in the proofs instead of laparoscopy in the below places.
PURPOSE: Endometriosis is a debilitating disease with high recurrence rates requiring long-term management. Progestins such as dienogest are used empirically when first symptoms occur and post-surgery to reduce recurrence. This retrospectiv…
BACKGROUND: Hysterectomy is the second most common operation in obstetrics and gynecology after Cesarean section. Until now, there has not been any German clinical guideline with recommendations concerning the indications for hysterectomy f…
OBJECTIVE: To demonstrate the superiority of estradiol valerate plus dienogest (E(2)V/DNG) over ethinylestradiol plus levonorgestrel (EE/LNG) in reducing the number of days with dysmenorrheic pain among women with primary dysmenorrhea. MET…
Endometriosis is one of the frequent gynecological diseases in premenopausal women. The clinical diagnostics is difficult because symptoms of endometriosis are variable. The surgical removal of endometriosis is the primary therapeutic aim. …
BACKGROUND: This double-blind trial investigated the efficacy and safety of estradiol valerate/dienogest (E(2)V/DNG) for the treatment of heavy menstrual bleeding without recognizable organic pathology. METHODS: Otherwise healthy women wit…
OBJECTIVE: A novel oral contraceptive (OC) that contains oestradiol valerate (E2V; 1 mg of E2V is equivalent to 0.76 mg of 17beta-oestradiol) and dienogest (DNG) has been developed. The efficacy and safety of this formulation was assessed i…
In Europa wird die Idee der Qualitätsverbesserung auf dem Gebiet der Endometriose vertieft. Verschiedene "Task Forces" arbeiten mit zum Teil identischen Methoden am gleichen Ziel. Die Bildung spezialisierter Endometriosezentren verbunden mi…
OBJECTIVE: To evaluate the efficacy, safety and tolerability of continuous combined hormone replacement therapy (HRT) with Climodien (estradiol valerate 2 mg plus dienogest 2 mg). DESIGN: Open, multinational, multicenter, non-controlled ph…
Objective To evaluate the efficacy, safety and tolerability of continuous combined hormone replacement therapy (HRT) with Climodien® (estradiol valerate 2 mg plus dienogest 2 mg). Design Open, multinational, multicenter, non-controlled phas…
OBJECTIVES: The aim of our study was to investigate the role of the intact endometrium and ovaries for serum levels of insulin-like growth factor binding protein-1 (IGFBP-1) and glycodelin. STUDY DESIGN: In 35 premenopausal patients with a…
Transvaginal hydrolaparoscopy (THL) was evaluated in comparison with the already established chromolaparoscopy in the detection of tubal factors, adhesions as well as endometriosis. 43 infertile patients without previous pelvic operations a…
Hysteroscopic surgery is widely used for the treatment of patients suffering from infertility and menorrhagia. Preoperative and postoperative treatment plays an important role in this kind of surgery. The indications for hormonal pre- and p…
If bleeding disorders, which could not be treated by modification of steroid dosages, occurred during sequential hormone replacement therapy (HRT), most of the patients stopped HRT. In these cases a diagnostic outpatient hysteroscopy with b…
OBJECTIVE: To determine the best pretreatment of the endometrium prior to roller ball endometrial ablation. STUDY DESIGN: Forty patients with recurrent hypermenorrhea underwent diagnostic hysteroscopy and dilation and curettage. They were …
The use of a 1.2 mm microendoscope is compared to the conventional laparoscopy technique in this study. In 22 sterility patients and 23 patients suffering from chronic pelvic pain the high diagnostic value of the microendoscope is shown. On…
In a prospective study in 40 patients the pretreatment for endometrial ablation with a gestagen (Orgametril 10 mg/die), danazol (600 mg/die) and an injection of a GnRH-analogon (Decapeptyl-Depot) was compared with a control group without pr…
13 months after a hysteroscopic endometrial ablation a haematometra was diagnosed in a 44 year-old women as a source of recurrent pelvic pain. The cause of the haematometra was a complete obliteration of the ostium cervicae internum. This l…