Charles C Coddington

STUDY QUESTION: Do women with polycystic ovary syndrome (PCOS) have a greater risk of adverse pregnancy complications (gestational diabetes, preeclampsia, cesarean section, placental abnormalities) and neonatal outcomes (preterm birth, smal…

BackgroundEndometriosis and uterine fibroids are common gynecologic conditions associated with a greater risk for infertility. Previous research has suggested that these conditions are associated with adverse pregnancy outcomes, potentially…

PurposeWe previously developed a subfertile comparison group with which to compare outcomes of assisted reproductive technology (ART) treatment. In this study, we evaluated whether insurance claims data in the Massachusetts All Payers Claim…

ObjectiveTo compare neonatal health outcomes after fresh versus frozen ET (FET).DesignRetrospective analysis of a population-based database of linked clinically assisted reproductive technology (ART) data with state vital records. Multivari…

PURPOSE: Pre-pregnancy and post-delivery hospitalizations were compared as markers for health among women who conceived using assisted reproductive technology (ART), non-ART medically assisted reproduction (MAR), no treatment (unassisted su…

Objective: Endometriosis impacts health-related quality of life. The objective was to assess the validity and responsiveness of the Health-Related Productivity Questionnaire, version 2 (HRPQ).Methods: Outcome measures (Endometriosis Health …

OBJECTIVES: Diagnostic delay is common in endometriosis. There is an unmet need for a symptom-based, patient-completed screening tool to facilitate discussions between patients and physicians about potential endometriosis symptoms. The obje…

PurposeThe aim of this study is to evaluate frequency of hospitalization before, during, and after assisted reproductive technology (ART) treatment by cycle outcome.MethodsSix thousand and one hundred thirty women residing in Massachusetts …

ObjectiveTo determine whether there is a correlation between preovulatory endometrial stripe thickness (EST) and pregnancy rates in clomiphene citrate (CC)/IUI cycles.DesignRetrospective cohort.SettingInfertility clinic of an academic medic…

BACKGROUND: Adenomyosis is rarely diagnosed before hysterectomy and commonly coexists with uterine leiomyomas. The objective of this study was to identify distinct features of a concurrent diagnosis of adenomyosis in women with uterine leio…

We report a case of an insulin-dependent diabetic female who received leuprolide acetate and Depo-Lurpon for the treatment of endometriosis. Their use was associated with hyperglycemia and a deterioration in glucose control that necessitate…

Although the exact etiology of endometriosis is unknown, several hypotheses about its origin exist. Of these, Sampson's theory of retrograde menstruation is the most widely accepted. Multiple in-vitro and in vivo models have been developed …

Read the full review for this Faculty Opinions recommended article: The effect of combined surgical-medical intervention on the progression of endometriosis in an adolescent and young adult population.

ObjectiveTo elucidate the clinical profile of adenomyosis by comparison with uterine leiomyomas.DesignRetrospective case-control study.SettingAcademic medical center.Patient(s)The study comprised 76 women undergoing hysterectomy with adenom…

Amenorrhea is a common symptom that generally presents to the gynecologist for evaluation and therapy during adolescence. Its presence, in combination with an anomaly of the vagina and a pelvic mass, suggests many possible etiologies whose …

In Brief OBJECTIVE To determine if exposure of human gametes to macrophage secretory products reduces sperm binding to the zona pellucida, and to determine which cytokine(s) may be responsible for this effect. METHODS A human macrophage cel…