OBJECTIVE: To determine whether assisted reproductive technology (ART) treatment adds obstetric and neonatal risks over and above that of underlying infertility-related diagnoses. DESIGN: Retrospective study of linked ART, birth certificat…
OBJECTIVE: To define specific risk factors for placenta previa in pregnancies conceived with assisted reproductive technology (ART). DESIGN: Retrospective cohort. SETTING: Fertility centers and inpatient obstetric units in Massachusetts. …
PurposeTo investigate assisted reproductive technology (ART) outcomes among adolescent and young-adult female cancer survivors.MethodsThe Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) data were lin…
ObjectiveTo investigate hospitalizations up to 8 years after live birth among women who used assisted reproductive technology (ART) or who were subfertile compared with women who conceived naturally.DesignRetrospective cohort.SettingDeliver…
STUDY QUESTION: Do women with polycystic ovary syndrome (PCOS) have a greater risk of adverse pregnancy complications (gestational diabetes, preeclampsia, cesarean section, placental abnormalities) and neonatal outcomes (preterm birth, smal…
BackgroundEndometriosis and uterine fibroids are common gynecologic conditions associated with a greater risk for infertility. Previous research has suggested that these conditions are associated with adverse pregnancy outcomes, potentially…
ObjectiveTo compare the obstetric and perinatal outcomes of deliveries conceived with embryos from single-step vs. sequential culture media systems.DesignHistorical cohort of Massachusetts vital records linked to assisted reproductive techn…
PurposeInvestigate the relationship between history of cancer and adverse pregnancy outcomes according to subfertility/fertility treatment.MethodsDeliveries (2004-2013) from Massachusetts (MA) Registry of Vital Records and Statistics were l…
BackgroundContemporary embryo biopsy in the United States involves the removal of several cells from a blastocyst that would become the placenta for preimplantation genetic testing. Embryos are then cryopreserved while patients await biopsy…
PurposeWe previously developed a subfertile comparison group with which to compare outcomes of assisted reproductive technology (ART) treatment. In this study, we evaluated whether insurance claims data in the Massachusetts All Payers Claim…
ObjectiveTo determine the maternal demographic, health, and fertility variables underlying prematurity.DesignRetrospective: Society for Assisted Reproductive Technology Clinic Outcome Reporting System data linked to Massachusetts birth cert…
ObjectiveTo evaluate the quantity and use of embryos cryopreserved at assisted reproductive technology (ART) clinics in the United States from 2004 through 2013 and to characterize trends in ART cycles in which all embryos were cryopreserve…
BackgroundAntimüllerian hormone is produced by small antral follicles and reflects ovarian reserve. Obesity is associated with lower serum antimüllerian hormone, but it is unclear whether lower levels of antimüllerian hormone in women with …
ObjectiveTo compare neonatal health outcomes after fresh versus frozen ET (FET).DesignRetrospective analysis of a population-based database of linked clinically assisted reproductive technology (ART) data with state vital records. Multivari…
PURPOSE: Pre-pregnancy and post-delivery hospitalizations were compared as markers for health among women who conceived using assisted reproductive technology (ART), non-ART medically assisted reproduction (MAR), no treatment (unassisted su…
ObjectivesTo assess the risk of adverse health outcomes for infants after assisted reproductive technology (ART)-treated and subfertile as compared with fertile deliveries.MethodsLive-born singleton infants ≥23 weeks' gestational age (GA) b…
BackgroundIt is unknown whether the risk of adverse outcomes in twin pregnancies among subfertile women, conceived with and without in vitro fertilization, differs from those conceived spontaneously.ObjectiveWe sought to evaluate the effect…
BackgroundAnecdotal evidence suggests that US practice patterns for ART differ by geographical region. The purpose of this study was to determine whether use of ICSI differs by region and to evaluate whether these rates are correlated with …
PurposeThe aim of this study is to evaluate frequency of hospitalization before, during, and after assisted reproductive technology (ART) treatment by cycle outcome.MethodsSix thousand and one hundred thirty women residing in Massachusetts …
BackgroundBirths to subfertile women, with and without infertility treatment, have been reported to have lower birthweights and shorter gestations, even when limited to singletons. It is unknown whether these decrements are due to parental …
Study questionHow do the assisted reproductive technology (ART) outcomes of women presenting for ART after cancer diagnosis compare to women without cancer?Summary answerThe likelihood of a live birth after ART among women with prior cancer…
ObjectiveTo evaluate pregnancy and birth outcomes by type of infertility treatment received.Study designAssisted reproductive technology (ART) data on women who were both treated and gave birth in Massachusetts were linked to vital records …