Effect of a Gonadotropin-Releasing Hormone Analogue on the Glucose Metabolism in a Diabetic Patient

Coddington Cc, C C Coddington, Charles C. Coddington, Hassiakos DK, D K Hassiakos, H C Harrison, Harrison HC, R G Brzyski, R Brzyski, Brzyski RG, G S Jones, Jones GS
Gynecologic and obstetric investigation · 2010 · vol. 30(4) , pp. 246–248 · doi:10.1159/000293279 · PMID:2127036 · W2053764212
article OA: closed CC0 ⤵ 3 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-13 ⓘ

Treatment of endometriosis with a GnRH analogue (leuprolide acetate/Depo-Lurpon) was associated with hyperglycemia and worsened glucose control in an insulin-dependent diabetic patient.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

We report a case of an insulin-dependent diabetic female who received leuprolide acetate and Depo-Lurpon for the treatment of endometriosis. Their use was associated with hyperglycemia and a deterioration in glucose control that necessitated changes in insulin dosage.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Antineoplastic Agents Blood Glucose Diabetes Mellitus, Type 1 Endometriosis Gonadotropin-Releasing Hormone Adult Antineoplastic Agents Blood Glucose Diabetes Mellitus, Type 1 Endometriosis Female Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Hormones Hormones Humans Leuprolide

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cited by (3)

Cited by (3)

Source provenance

europepmc
last seen: 2026-08-22T06:09:51.966504+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:12:15.619952+00:00
unpaywall
last seen: 2026-08-22T06:23:50.750314+00:00
License: CC0 · commercial use OK