A gonadotropin-releasing hormone analogue impairs glucose tolerance in a diabetic patient

Imai A, Atsushi Imai, A Imai, A Takagi, Atsushi Takagi, Takagi A, Shinji Horibe, Horibe S, S Horibe, T Fuseya, Tatsuo Fuseya, Fuseya T, Hiroshi Takagi, Takagi H, H Takagi, Teruhiko Tamaya, T Tamaya, Tamaya T
European journal of obstetrics, gynecology, and reproductive biology · 1998 · vol. 76(1) , pp. 121–122 · doi:10.1016/s0301-2115(97)00158-9 · PMID:9481560 · W2002550259
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This paper describes a gonadotropin-releasing hormone analogue that impaired glucose tolerance in a diabetic patient.

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Abstract

Changes in serum glucose levels were examined in a female with insulin-independent diabetes who received a gonadotropin-releasing hormone (GnRH) analog treatment for pelvic endometriosis. The mean blood glucose levels were higher on busereline therapy, and higher levels of hemoglobin A1c were noted on busereline therapy (range 6.9-12.5%) versus pre- and post-treatment (range 5.1-5.9%). Hormonal alteration induced by GnRH analog treatment may impair glucose tolerance.

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Condition tags

endometriosis

MeSH descriptors

Blood Glucose Buserelin Diabetes Mellitus, Type 1 Endometriosis Adult Blood Glucose Buserelin Buserelin Danazol Danazol Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 1 Endometriosis Endometriosis Estrogen Antagonists Estrogen Antagonists Female Glycated Hemoglobin Glycated Hemoglobin Humans

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