Mekan R. Orazov

Multimorbidity is a key global trend across healthcare fields, including gynecology. It is strongly associated with an overall poorer health status. Statistics indicate that in the 21st century most women experience at least one gynecologic…

Rapid technological development has allowed the creation of artificial intelligence (AI). Currently, researchers are trying to implement its models in various fields of medicine, including gynecology. Is AI a “panacea” or merely a promising…

Endometriosis still remains one of the most interesting but poorly understood disease entities in the world. The current epidemiological research data demonstrate that the endometriosis incidence rate will soon become somewhat of a pandemic…

Endometriosis is now recognized as a significant issue in the global health system. According to the available data, endometriosis affects women not only of reproductive age, but also other age cohorts. Recent studies demonstrate that the c…

Endometriosis remains one of the key challenges in reproductive medicine in the 21st century. One in ten women of reproductive age has this condition, the main clinical manifestations of which are chronic pelvic pain and infertility. It sho…

The search for approaches to diagnosing and treating endometriosis remains a priority in modern gynecology. The extremely high prevalence of this condition and its detrimental effect on somatic and reproductive health and the quality of lif…

Introduction. Long-term chronic inflammation in the endometrium leads to sclerotic changes, disorders in the extracellular matrix and intercellular interactions, and, ultimately, to impaired formation of spiral arteries and hypoperfusion. T…

Chronic endometritis is widespread among women of reproductive age, it can be the cause of menstrual disorders, abnormal uterine bleeding and, finally, infertility of uterine genesis. The issue of impaired immune status of the glandular-str…

Significant changes in the lifestyle of the global population at present (in particular, the high prevalence of metabolic syndrome) have led to a “spike” in the incidence of proliferative endometrial diseases. A “strong” pathogenetic associ…

Abnormal uterine bleeding (AUB), common in a cohort of women in the reproductive period, is undoubtedly an extremely important factor reducing quality of life. Persistent endometrial inflammation is a pathogenetic link associated with endom…

Endometriosis remains one of the most controversial diseases in modern gynecology. Many new discoveries regarding the pathogenesis of endometriosis raise even more questions in terms of therapeutic approaches to this nosology. According to …

Endometriosis remains one of the most mysterious and controversial diseases in modern gynecology. Contemporary statistical data demonstrate the extreme relevance of actively implementing effective therapeutic approaches into the clinician’s…

Currently, endometriosis is one of the most common and relevant gynecological conditions. It is characterized by a wide range of symptoms, with highly heterogeneous pain being one of the most typical. The unifying concept of the algological…

Endometriosis is still one of the most mysterious and urgent gynecological diseases. The prevalence of endometriosis is steadily increasing, despite the development of innovative methods of diagnosis and treatment. Endometriosis is the pres…

Objective. Objective of this review is the systematic analysis and summarization the scientifc data available in the current literature on the predictive approach to the management of women with endometrial hyperplasia without atypia. Mater…

Violation of the receptivity of the endometrium in adenomyosis can be supported either by pathological processes in the structure of the endometrium, such as an unexpected increase in vascularization and thickness of the endometrial stroma …

Relevance. The identification of the relationship between adenomyosis and infertility, as well as the possible overcoming of the consequences, is one of the main tasks of reproduction. Despite the fact that adenomyosis is more often detecte…

Aim. To identify risk factors for in vitro fertilization (IVF) failures in women with adenomyosis-associated infertility. Materials and methods. The study included 83 patients of reproductive age with adenomyosis. Women were divided into t…

Endometrial polyp (EP) is a frequent incidental finding during hysteroscopy in asymptomatic patients. To date, the pathogenesis of EPs has not been fully disclosed, which challenges the primary and secondary prevention of EPs and their targ…

Endometrial polyp (EP) is a frequent incidental finding during hysteroscopy in asymptomatic patients. To date, the pathogenesis of EPs has not been fully disclosed, which challenges the primary and secondary prevention of EPs and their targ…

Background. Ovarian endometriosis has the most aggressive effect on the ovarian reserve compared to other types of benign ovarian neoplasms. Laparoscopic cystectomy with pathomorphological verification remains the gold standard for the diag…