Li J

Adult endometrial glands undergo cyclic regeneration and development during the menstrual cycle. Their secretions are vital for endometrial functions and early pregnancy, yet the mechanisms controlling gland development are not well underst…

PURPOSE: To systematically evaluate and compare the quality, readability, and query-model consistency of adenomyosis-related content generated by two large language models, ChatGPT (GPT-5) and DeepSeek (R1). MATERIALS AND METHODS: In total…

Objectives: This research sought to examine the impact of gossypol on cervical cancer tumors that have been transplanted subcutaneously in nude mice, as well as the associated risk of liver damage and its underlying mechanisms. Methods: A s…

Phthalate esters (PAEs) and organophosphate esters (OPEs) are pervasive 20 environmental pollutants with endocrine-disrupting properties. Despite growing 21 evidence linking PAE/OPE exposure to female reproductive disorders, the 22 diseases…

Despite ongoing challenges in developing effective non-surgical and non-hormonal treatments for endometriosis, the psychological manifestations of the disease-particularly anxiety-remain comparatively underexplored. In this study, a hydroge…

This study aimed to investigate how levels of serum follicle-stimulating hormone (FSH) on Day 7 of ovarian stimulation are related to the number of oocytes retrieved, and identify any cutoff or threshold point in protocols using gonadotropi…

BackgroundSarcopenia, an age-correlated decline in skeletal muscle mass and function, has been increasingly linked to ferroptosis, which is an iron-dependent form of regulated cell death driven by lipid peroxidation. Nevertheless, the diagn…

BACKGROUND: N6-methyladenosine (m6A) modification regulates the processes of RNA splicing, subcellular localization, translation and stability by changing the RNA structure and the interaction between RNA and RNA-binding proteins to ensure …

Poor ovarian response (POR) constitutes a notable clinical challenge within the domain of assisted reproductive technology, primarily attributable to the lack of reliable biomarkers for precise diagnosis and treatment. This study reveals si…

BACKGROUND: Endometrial cancer (EC) is one of the most common malignant tumors in women, and in recent years, the role of gut microbiota in tumorigenesis has gradually gained attention. Previous studies have shown that the gut microbiome is…

ImportanceTonsillectomy has long been scrutinized for its potential long-term impacts on health, with conflicting evidence linking it to increased risks of several diseases, such as cancer, psychiatric disorders, and immune dysfunctions.Obj…

The paradigm shift of lactate from a mere metabolic byproduct to a pleiotropic signaling molecule, coupled with the discovery of lactylation, provides a crucial framework for understanding how metabolic reprogramming drives systemic patholo…

ObjectiveBy using the propensity score matching (PSM) method, this study compared the pregnancy outcomes of two ovulation induction regimens, clomiphene citrate (CC) and letrozole (LE), in intrauterine insemination (IUI) cycles. It aimed to…

BACKGROUND: Endometriosis is a chronic inflammatory disease characterized by immune microenvironment dysregulation, with the IL-33/ST2L signaling axis playing a crucial role in macrophage polarization and disease progression. Despite growin…

We report a rare case of Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome accompanied by simultaneous adenomyosis and leiomyoma in rudimentary uterine remnants. A 35-year-old woman presented with progressive lower abdominal pain and underwent…

Wen Shi,1– 3,* Minyi Wang,1– 3,* Zhuang Jin,1– 3 Xiaochuan Chen,1– 3 Jinbo Li,1– 3 Huiling Lai,1– 3 Xiao Li,1– 3 Qiyu Zhong,1– 3 Ye Chen,1– 3 Shuqin Chen1– 3 1Department of Gynecology, The Sixth Affiliated Hospital, Sun Yat-sen Univ…

BACKGROUND: Endometriosis (EMS) is characterized by pain symptoms that seriously affect patients' quality of life. Gut microbiome-related metabolites (GMRM) play an important role in the process of EMS. However, the role of GMRM in endometr…

Wen Shi,1–3,* Minyi Wang,1–3,* Zhuang Jin,1–3 Xiaochuan Chen,1–3 Jinbo Li,1–3 Huiling Lai,1–3 Xiao Li,1–3 Qiyu Zhong,1–3 Ye Chen,1–3 Shuqin Chen1–3 1Department of Gynecolog…

Macrophages, key players in the immune system, exhibit remarkable plasticity, polarizing into pro-inflammatory (M1) or anti-inflammatory (M2) phenotypes in response to microenvironmental cues. This functional dichotomy is pivotal in the pat…

INTRODUCTION: Endometriosis is a chronic, estrogen-dependent gynecological disorder affecting approximately 10% of women worldwide that can cause pelvic pain, lead to infertility, and impair quality of life. Whether the condition elevates r…

Jing Li,1 Yang Yang,2 Teng Li,1 Bowei Sun,3 Yongai Zhang1 1Department of Nursing and Rehabilitation College, Xi’an Medical University, Xi’an, Shaanxi, 710021, People’s Republic of China; 2Department of Reproductive Medicine, Xi’an People’s …

ObjectiveTo explore the correlation between autoantibodies, ultrasonic endometrial receptivity parameters and early miscarriage in recurrent spontaneous abortion (RSA) patients during subsequent pregnancies, and to establish and validate a …