BMC women's health

BACKGROUND: Pain is the primary symptom of endometriosis and may progress into a chronic, acyclic condition driven by neuroinflammatory mechanisms, leading to neuropathic and ultimately nociplastic pain. Central sensitization, a form of noc…

A teenage girl presented with sudden lower abdominal pain following exercise, prompting initial consideration of ovarian cyst rupture by the attending emergency physician. However, the presence of unilateral renal absence on Computed Tomogr…

BACKGROUND: In recent years, microRNAs have attracted increasing attention for their potential diagnostic and prognostic value across various diseases. This systematic review and meta-analysis aimed to evaluate the diagnostic accuracy of mi…

OBJECTIVES: To compare the differences in clinical characteristics between different types of abdominal wall endometriosis (AWE) according to the invasive levels of tissue mass. METHODS: 122 patients, who had undergone resection of AWE les…

BACKGROUND: Anhedonia, a diminished response to pleasurable stimuli extensively studied in mental disorders and chronic pain, has been reported as prevalent among patients with deep endometriosis. Anhedonia is considered a multifaceted tran…

BACKGROUND: Synchronous multiple primary malignancies (SMPMs) involving the uterus and ovary pose significant diagnostic challenges, particularly in distinguishing independent primary tumors from metastatic disease when tumors exhibit overl…

BACKGROUND: Endometriosis is a chronic condition affecting women of reproductive age and often associated with pain, impaired fertility, and reduced quality of life. Management requires long-term strategies, with medical treatment preferred…

BACKGROUND: Adenomyosis frequently coexists with other gynecological diseases, but the full spectrum of comorbidities and malignant conditions in surgically treated patients remain uncharacterized. This study sought to delineate concurrent …

OBJECTIVE: This study aimed to determine the prevalence of polycystic ovary syndrome (PCOS) co-occurrence in a clinical population of women with endometriosis and to quantitatively assess its impact on infertility, symptom severity, and qua…

BACKGROUND: Abnormal uterine bleeding (AUB) is a common gynecological condition with a significant impact on women’s quality of life and public health. Although the levonorgestrel-releasing intrauterine system (LNG-IUS) is an effective firs…

BACKGROUND: Endometriosis of the canal of Nuck is an extremely rare manifestation of extrapelvic endometriosis that may mimic common groin pathologies such as inguinal hernia or hydrocele, often leading to diagnostic difficulty and delayed …

BACKGROUND: Endometriosis (EMs) is a prevalent gynecological disorder among women of reproductive age. HAGLR has recently been identified as a potential factor in EMs, but its functional role and underlying mechanisms remain unclear. METHO…

RESEARCH QUESTION: Endometriosis-related chronic pain leads to impaired health-related quality of life (HRQoL). Endometriosis surgery can improve chronic pain and HRQoL, however, pain complaints often remain and HRQoL is still lower compare…

BACKGROUND: Ovarian endometriosis(OEM) is a highly prevalent condition that significantly affects women’s health. Tissue-derived extracellular vesicles(Ti-EVs) contain multiple molecules that maintain intercellular communication. They parti…

OBJECTIVE: To evaluate the long-term therapeutic efficacy of uterine artery embolization (UAE) for adenomyosis and to identify independent prognostic factors associated with postoperative recurrence. METHODS: A total of 200 adenomyosis pat…

BACKGROUND: Laparoscopic ovarian cystectomy for endometriosis carries a substantial risk of diminished ovarian reserve. Optimal intraoperative hemostasis remains uncertain, and predictive tools for postoperative ovarian function are limited…

BACKGROUND: Endometriosis is a benign chronic gynecological disease in women of reproductive age. However, patient satisfaction with medical care for endometriosis in Germany remains underresearched. Therefore, this study aims to describe t…

OBJECTIVE: This study aims to investigate the efficacy of novel embolic materials in the treatment of adenomyosis via partial embolization of uterine arteries. METHODS: From June 2023 to June 2025, we used gelatin sponge particles, liquid …

BACKGROUND: Endometriosis is a prevalent chronic condition that causes persistent pelvic pain, significantly impairing quality of life and contributing to psychological distress. This study aimed to assess the prevalence of clinically signi…

BACKGROUND: Migraine and endometriosis are both debilitating chronic pain conditions that frequently co-occur in women. We aimed to assess the prevalence of migraine in women with surgically confirmed endometriosis (SCE) compared to women w…