BMC women's health

BACKGROUND: Endometriosis is an estrogen-dependent benign inflammatory disorder characterized by the implantation of active endometrial tissue (glands or stroma) outside the uterus, with pelvic adhesions as a core hallmark. Omental endometr…

BACKGROUND: Heavy menstrual bleeding (HMB) is common in the general population, affecting at least one-quarter of women of reproductive age. A bleeding disorder has been reported as an underlying cause of HMB in 30% of hospital-based outpat…

BackgroundAbdominal incisions are mostly done in the umbilical or suprapubic regions, typically in the midline, to prevent visceral and vascular injury, by taking advantage of the greater distance between these incision sites and the intraa…

BackgroundThe adverse impacts of homeostasis disturbance of plasma trace elements on female reproduction, including premature ovarian insufficiency (POI), have received increasing attention recently, yet limited evidence has been reported s…

BACKGROUND: Endometriosis (EMS) is a prevalent gynecological condition, and its diagnosis remains challenging. Hematological indicators such as platelet count (PLT), mean platelet volume (MPV), and platelet-to-lymphocyte ratio (PLR) have re…

BACKGROUND: Circadian rhythm disturbances are known to impair ovarian reserve through endocrine and molecular pathways. However, the specific impact of daytime napping as a common compensatory sleep behavior remains poorly understood. METHO…

BACKGROUND: Menstrual health symptoms, including painful periods, heavy bleeding, and premenstrual syndrome (PMS), are prevalent in midlife women and may be influenced by lifestyle factors. Identifying modifiable health behaviours associate…

BackgroundOvarian clear cell carcinoma (OCCC) is a distinct subtype of epithelial ovarian cancer with characteristic biological behavior and clinical features. Accurate preoperative staging is essential for guiding optimal management; howev…

ObjectiveFemale reproductive diseases (FRDs) impose a substantial health burden. Observational studies suggest links between oral dysbiosis and systemic conditions, but whether oral microbial traits causally influence FRDs remains unclear. …

BACKGROUND: Pain is the primary symptom of endometriosis and may progress into a chronic, acyclic condition driven by neuroinflammatory mechanisms, leading to neuropathic and ultimately nociplastic pain. Central sensitization, a form of noc…

Background/objectivesThis study aimed to determine the distribution of confirmed urological diagnoses in female patients presenting with flank pain and to evaluate the diagnostic performance of clinical, laboratory, and imaging parameters i…

BACKGROUND: Ureteral endometriosis with hydroureteronephrosis can impair renal function, yet few clear guidelines exist for its surgical treatment. This study aimed to compare the clinicopathological features between patients undergoing ure…

BackgroundSynchronous endometrioid endometrial and ovarian carcinomas (SEEOCs) represent a small yet clinically significant entity of gynecological malignancies. Their clinicopathological correlations, immunohistochemical profiles, and prog…

BACKGROUND: Endometriosis is a common chronic disease in women of reproductive age, and long-term postoperative medical management is a key strategy for preventing recurrence. Currently used clinical medications include dienogest (DNG), GnR…

BACKGROUNDS: The levonorgestrel-releasing intrauterine system (LNG-IUS) is an effective treatment for adenomyosis; however, its therapeutic benefits are frequently limited by a high expulsion risk. This study aimed to compare the safety and…

BackgroundLaparoscopic myomectomy carries a risk of significant intraoperative bleeding. Although uterine artery occlusion is used to reduce blood loss, its overall benefit compared with no occlusion and the relative performance of differen…

ObjectiveWe compared the surgical outcomes and quality of recovery of conventional multiport laparoscopy (CML), Single-port laparoscopy (SPL), and vaginal natural orifice transluminal endoscopic surgery (vNOTES) for managing large adnexal m…

Background and aimsWe compared four imaging methods: transvaginal ultrasound(TVU), magnetic resonance imaging(MRI), saline contrast-enhanced MRI (SCE_MRI) and hysteroscopy combined with transabdominal ultrasound (HSC_TAU) for evaluating ces…

BackgroundHysterectomy is one of commonly performed gynaecological surgeries. Even though it is effective for treating benign conditions, it can compromise ovarian function by disrupting blood supply, potentially leading to earlier menopaus…

BACKGROUND: Deep infiltrating endometriosis (DIE) is a rare and severe subtype of endometriosis that can cause marked distortion of pelvic anatomy. Diagnosis becomes particularly challenging when it presents as an acute abdomen with signifi…

BACKGROUND: Total fertilization failure (TFF) and embryo developmental arrest (EDA) remain clinically challenging outcomes in intracytoplasmic sperm injection (ICSI) cycles. Although ICSI is widely and effectively used to overcome fertiliza…

A teenage girl presented with sudden lower abdominal pain following exercise, prompting initial consideration of ovarian cyst rupture by the attending emergency physician. However, the presence of unilateral renal absence on Computed Tomogr…

BACKGROUND: In recent years, microRNAs have attracted increasing attention for their potential diagnostic and prognostic value across various diseases. This systematic review and meta-analysis aimed to evaluate the diagnostic accuracy of mi…

OBJECTIVES: To compare the differences in clinical characteristics between different types of abdominal wall endometriosis (AWE) according to the invasive levels of tissue mass. METHODS: 122 patients, who had undergone resection of AWE les…

BACKGROUND: Anhedonia, a diminished response to pleasurable stimuli extensively studied in mental disorders and chronic pain, has been reported as prevalent among patients with deep endometriosis. Anhedonia is considered a multifaceted tran…