BMC women's health

BACKGROUND: Endometriosis is an estrogen-dependent benign inflammatory disorder characterized by the implantation of active endometrial tissue (glands or stroma) outside the uterus, with pelvic adhesions as a core hallmark. Omental endometr…

BACKGROUND: Heavy menstrual bleeding (HMB) is common in the general population, affecting at least one-quarter of women of reproductive age. A bleeding disorder has been reported as an underlying cause of HMB in 30% of hospital-based outpat…

BACKGROUND: Endometriosis (EMS) is a prevalent gynecological condition, and its diagnosis remains challenging. Hematological indicators such as platelet count (PLT), mean platelet volume (MPV), and platelet-to-lymphocyte ratio (PLR) have re…

BACKGROUND: Circadian rhythm disturbances are known to impair ovarian reserve through endocrine and molecular pathways. However, the specific impact of daytime napping as a common compensatory sleep behavior remains poorly understood. METHO…

BACKGROUND: Menstrual health symptoms, including painful periods, heavy bleeding, and premenstrual syndrome (PMS), are prevalent in midlife women and may be influenced by lifestyle factors. Identifying modifiable health behaviours associate…

BACKGROUND: Pain is the primary symptom of endometriosis and may progress into a chronic, acyclic condition driven by neuroinflammatory mechanisms, leading to neuropathic and ultimately nociplastic pain. Central sensitization, a form of noc…

BACKGROUND: Ureteral endometriosis with hydroureteronephrosis can impair renal function, yet few clear guidelines exist for its surgical treatment. This study aimed to compare the clinicopathological features between patients undergoing ure…

BACKGROUND: Endometriosis is a common chronic disease in women of reproductive age, and long-term postoperative medical management is a key strategy for preventing recurrence. Currently used clinical medications include dienogest (DNG), GnR…

BACKGROUNDS: The levonorgestrel-releasing intrauterine system (LNG-IUS) is an effective treatment for adenomyosis; however, its therapeutic benefits are frequently limited by a high expulsion risk. This study aimed to compare the safety and…

BackgroundHysterectomy is one of commonly performed gynaecological surgeries. Even though it is effective for treating benign conditions, it can compromise ovarian function by disrupting blood supply, potentially leading to earlier menopaus…

BACKGROUND: Deep infiltrating endometriosis (DIE) is a rare and severe subtype of endometriosis that can cause marked distortion of pelvic anatomy. Diagnosis becomes particularly challenging when it presents as an acute abdomen with signifi…

BACKGROUND: Total fertilization failure (TFF) and embryo developmental arrest (EDA) remain clinically challenging outcomes in intracytoplasmic sperm injection (ICSI) cycles. Although ICSI is widely and effectively used to overcome fertiliza…

A teenage girl presented with sudden lower abdominal pain following exercise, prompting initial consideration of ovarian cyst rupture by the attending emergency physician. However, the presence of unilateral renal absence on Computed Tomogr…

BACKGROUND: In recent years, microRNAs have attracted increasing attention for their potential diagnostic and prognostic value across various diseases. This systematic review and meta-analysis aimed to evaluate the diagnostic accuracy of mi…

OBJECTIVES: To compare the differences in clinical characteristics between different types of abdominal wall endometriosis (AWE) according to the invasive levels of tissue mass. METHODS: 122 patients, who had undergone resection of AWE les…

BACKGROUND: Anhedonia, a diminished response to pleasurable stimuli extensively studied in mental disorders and chronic pain, has been reported as prevalent among patients with deep endometriosis. Anhedonia is considered a multifaceted tran…

BACKGROUND: Synchronous multiple primary malignancies (SMPMs) involving the uterus and ovary pose significant diagnostic challenges, particularly in distinguishing independent primary tumors from metastatic disease when tumors exhibit overl…

BACKGROUND: Spontaneous ovarian endometrioma rupture typically presents with acute abdominal pain, a condition often complicated by tissue edema and pelvic adhesions that increase surgical difficulty. This study aims to evaluate the impact …

BACKGROUND: Early-life exposures may influence long-term reproductive health, but comprehensive population-based evidence remains limited. This study aimed to evaluate the associations between six early-life factors (long-term/recurrent ant…

BACKGROUND: E-cigarette use (vaping) is rapidly increasing among women of reproductive age, with an estimated one in five women aged 15-45 now using e-cigarettes in England. Despite being promoted as a safer alternative to cigarettes, the r…

OBJECTIVE: To investigate the effect of bisphosphonates on surgical site infection (SSI) and their safety in postmenopausal women undergoing Anterior Cervical Discectomy and Fusion (ACDF). METHODS: This was a single-center retrospective coh…

BACKGROUND: Minimally invasive surgical techniques have transformed disease management paradigms; however, laparoscopy remains associated with significant post-operative morbidity. Approximately 80% of patients report severe shoulder pain w…

BACKGROUND: We aimed to study the impact of centralizing surgical endometriosis care, including possible improvements in patient outcome. METHODS: This study is a single tertiary centre retrospective cohort study with a 3-year postoperativ…

BACKGROUND: Pelvic floor myofascial pain (PFMP) is a common cause of chronic pelvic pain. We aimed to explore whether the application of extracorporeal shockwave therapy (ESWT) is associated with reductions in pain intensity and pelvic floo…

BACKGROUND: Endometriosis is a chronic condition affecting women of reproductive age and often associated with pain, impaired fertility, and reduced quality of life. Management requires long-term strategies, with medical treatment preferred…