BACKGROUND: Anhedonia, a diminished response to pleasurable stimuli extensively studied in mental disorders and chronic pain, has been reported as prevalent among patients with deep endometriosis. Anhedonia is considered a multifaceted tran…
BACKGROUND: Synchronous multiple primary malignancies (SMPMs) involving the uterus and ovary pose significant diagnostic challenges, particularly in distinguishing independent primary tumors from metastatic disease when tumors exhibit overl…
BACKGROUND: Spontaneous ovarian endometrioma rupture typically presents with acute abdominal pain, a condition often complicated by tissue edema and pelvic adhesions that increase surgical difficulty. This study aims to evaluate the impact …
BACKGROUND: Early-life exposures may influence long-term reproductive health, but comprehensive population-based evidence remains limited. This study aimed to evaluate the associations between six early-life factors (long-term/recurrent ant…
BACKGROUND: E-cigarette use (vaping) is rapidly increasing among women of reproductive age, with an estimated one in five women aged 15-45 now using e-cigarettes in England. Despite being promoted as a safer alternative to cigarettes, the r…
OBJECTIVE: To investigate the effect of bisphosphonates on surgical site infection (SSI) and their safety in postmenopausal women undergoing Anterior Cervical Discectomy and Fusion (ACDF). METHODS: This was a single-center retrospective coh…
BACKGROUND: The impact of long-acting reversible contraception (LARC) on female sexual function remains a controversial and often overlooked issue. This study aimed to evaluate the effects of three common LARC methods on female sexual funct…
BACKGROUND: Breathing exercises may modulate dysmenorrhea by enhancing relaxation and eliciting analgesic effects. This study investigated the effects of Pelvic Floor Muscle Training (PFMT) with or without Dynamic Neuromuscular Stabilizatio…
BACKGROUND: Minimally invasive surgical techniques have transformed disease management paradigms; however, laparoscopy remains associated with significant post-operative morbidity. Approximately 80% of patients report severe shoulder pain w…
BACKGROUND: We aimed to study the impact of centralizing surgical endometriosis care, including possible improvements in patient outcome. METHODS: This study is a single tertiary centre retrospective cohort study with a 3-year postoperativ…
BACKGROUND: Pelvic floor myofascial pain (PFMP) is a common cause of chronic pelvic pain. We aimed to explore whether the application of extracorporeal shockwave therapy (ESWT) is associated with reductions in pain intensity and pelvic floo…
BACKGROUND: Endometriosis is a chronic condition affecting women of reproductive age and often associated with pain, impaired fertility, and reduced quality of life. Management requires long-term strategies, with medical treatment preferred…
BACKGROUND: Adenomyosis frequently coexists with other gynecological diseases, but the full spectrum of comorbidities and malignant conditions in surgically treated patients remain uncharacterized. This study sought to delineate concurrent …
OBJECTIVE: This study aimed to determine the prevalence of polycystic ovary syndrome (PCOS) co-occurrence in a clinical population of women with endometriosis and to quantitatively assess its impact on infertility, symptom severity, and qua…
BACKGROUND: The management of endometriomata remains a challenge, with current options associated with either high recurrence rates or significant reduction in ovarian reserve. Ethanol sclerotherapy has been suggested as a treatment that is…
BACKGROUND: Regenerative remodeling of the pelvic floor after labor and delivery restores pelvic organ positioning. In some individuals, accumulated tissue damage leads to failure of support structures, including the uterosacral ligament (U…
BACKGROUND: Abnormal uterine bleeding (AUB) is a common gynecological condition with a significant impact on women’s quality of life and public health. Although the levonorgestrel-releasing intrauterine system (LNG-IUS) is an effective firs…
INTRODUCTION: Cervical stenosis (CS) is a condition characterized by the narrowing of the cervical canal, which can lead to complications such as pyometra and fallopian tube torsion (FTT). The interplay of these conditions is rarely documen…
BACKGROUND: Cesarean delivery often results in both abdominal wall scars and uterine scars. However, current rehabilitation strategies for cesarean-related scars lack standardization and a biomechanically informed framework that integrates …
BACKGROUND: Endometriosis of the canal of Nuck is an extremely rare manifestation of extrapelvic endometriosis that may mimic common groin pathologies such as inguinal hernia or hydrocele, often leading to diagnostic difficulty and delayed …
Endometriosis is a chronic gynecological disorder characterized by ectopic tissue growth and significant morbidity, yet current hormonal and surgical treatments often fail to prevent recurrence or entail severe side effects. Increasing evid…
BACKGROUND: Device expulsion is a common complication of the levonorgestrel-releasing intrauterine system (LNG-IUS), with a higher incidence among high-risk patients presenting with enlarged uterine cavities, cervical laxity or menorrhagia.…
BACKGROUND: Endometriosis (EMs) is a prevalent gynecological disorder among women of reproductive age. HAGLR has recently been identified as a potential factor in EMs, but its functional role and underlying mechanisms remain unclear. METHOD…
OBJECTIVE: Chronicpelvic pain is a multifactorial condition that significantly impacts women’s quality of life. Pelvic venous disorders (PeVD) are increasingly recognized as a potential contributor to chronic pelvic pain and are related to …
BACKGROUND: Expulsion of the levonorgestrel-releasing intrauterine system (LNG-IUS) limits its effectiveness in adenomyosis management, particularly in patients with anatomical risk factors. This study aimed to assess the feasibility and sh…