Yutaka Osuga
No ORCID on file
· 275 papers in corpus
· active 1995-2026
Study types
- article 199
- other 29
- review 13
- preprint 10
- book-chapter 7
Condition tags
- endometriosis 201
- adenomyosis 54
- endometrioma 38
- dysmenorrhea 28
- infertility 24
- chronic_pelvic_pain 11
- dyspareunia 5
- bowel_endometriosis 4
- bladder_endometriosis 3
- mesh:D004716 3
Top journals
Frequent coauthors
- Oikawa Y 177
- Kaori Azuma Koga 156
- Yasushi Hirota 133
- Tomoyuki Hirata 113
- Miyuki Harada 109
- Tomoyuki Fujii 75
- Yojiro Taketani 75
- Osamu Yoshino 71
- Taketani Y 62
- Osamu Wada-Hiraike 55
article
2008
BACKGROUND: The increase in concentration of osteoprotegerin, an antagonist of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), in the peritoneal fluid of women with endometriosis may interfere with TRAIL-induced apoptosis i…
article
2007
ObjectiveTo describe a case report of hydrosalpinx that changed dramatically in size during the menstrual cycle.DesignCase report.SettingUniversity teaching hospital reproductive endocrinology and infertility practice.Patient(s)A 32-year-ol…
article
2007
ObjectiveTo investigate the effect of dienogest on the proliferation of endometriotic stromal cells.DesignComparative and laboratory study.SettingUniversity of Tokyo Hospital.Patient(s)Endometriotic stromal cells were isolated and cultured …
article
2007
Aim: Hysterosalpingography (HSG) is one of the most commonly used methods in order to evaluate the condition of fallopian tubes in infertility clinics. In the present paper, we retrospectively compared the findings of HSG and laparoscopy to…
article
2007
The concentration of the soluble form of CD44, a competitive inhibitor for CD44 and hyaluronic acid binding, is higher in the peritoneal fluid of patients with endometriosis than in the peritoneal fluid of patients without endometriosis.
article
2007
article
2007
IL-17A is secreted from Th17 cells, a discovery leading to revision of the mechanism underlying the role of Th1/Th2 in the immune response. Strong evidence suggests that immune responses associated with inflammation are involved in the path…
article
2007
CONTEXT: Metformin, a widely used treatment for diabetes that improves insulin sensitivity, also has both antiinflammatory properties and a modulatory effect on ovarian steroid production, two actions that have been suggested to be efficaci…
article
2006
We describe a 37-year-old woman with giant cystic adenomyosis who underwent a hysterectomy, providing magnetic resonance imaging and gross and microscopic images.
article
2006
article
2006
article
2006
Adiponectin, a pleiotropic cytokine, exerts its effects via the specific receptors AdipoR1 and AdipoR2. Whereas circulating adiponectin concentrations decrease in women with endometriosis and endometrial cancer, possible effects of adiponec…
article
2006
In various cells including endometriotic cells, p38 mitogen-activated protein kinase (MAPK) plays essential roles for inflammation, an etiological factor for endometriosis. We evaluated the effect of FR 167653, a p38 MAPK inhibitor, on the …
article
2006
Both the classic form of the gonadotropin-releasing hormone receptor, GnRH I, and GnRH agonists reportedly have antiproliferative and apoptotic (programmed cell death) effects on cultured endometriotic cells as well as on some cancer cells …
article
2006
article
2006
BACKGROUND: To analyse risk factors that influence the recurrence of endometrioma after laparoscopic excision. METHODS: A total of 224 patients who had a minimum of 2 years of post-operative follow-up after laparoscopic ovarian endometrioma…
article
2005
BACKGROUND: Inflammation has been proposed to play essential roles in the pathophysiology of endometriosis, in which neutrophils and mast cells have been suggested to be involved. We studied whether the protease-activated receptor 2 (PAR2),…
article
2005
PROBLEM: Adiponectin is a novel adipocytokine of extreme importance for the metabolism. Recent studies have indicated that adiponectin suppresses inflammation, angiogenesis, and fibrosis, which are central pathogenic factors for endometrios…
article
2005
BACKGROUND: Aiming at improving an animal model of endometriosis, we developed a homologous mouse model using 'green mice' that ubiquitously express green fluorescent protein. METHODS: Endometrial fragment obtained from estradiol (E2)-suppl…
other
2005
OBJECTIVE: To investigate the role of interleukin (IL)-16 in peritoneal fluid in the pathogenesis of endometriosis. DESIGN: Comparative and laboratory study. SETTING: University of Tokyo Hospital. PATIENT(S): Peritoneal fluids (PFs) were…
article
2005
BACKGROUND: GnRH II is the second form of GnRH and is widely distributed in peripheral tissues of the female reproductive tract as well as in the central nervous system. In the present study, we studied the possible implication of GnRH II i…
article
2005
Uterine movement is suggested to play roles in various events related to the uterus. In view of the current concept underscoring the biological implications of mechanical stretch, we speculated that the mechanical stretch exerted by uterine…
article
2005
BACKGROUND: The present study was conducted to assess whether midkine (MK), a multifunctional molecule known to stimulate tumor growth, may be involved in the development of endometriosis. METHODS: The mitogenic activity of MK on cultured e…
article
2005
Endometriosis is known to be associated with local inflammatory reactions. Given the emerging concept of thrombin and its specific receptor, protease-activated receptor 1 (PAR1), as important players in inflammation and cell proliferation, …
article
2005
ObjectiveTo report a case of sciatic endometriosis diagnosed by computerized tomography (CT)-guided biopsy in combination with CD10 immunohistochemical staining.DesignCase report.SettingUniversity hospital.Patient(s)A 33-year-old Japanese w…