Yutaka Osuga

No ORCID on file · 275 papers in corpus · active 1995-2026

Study types

  • article 199
  • other 29
  • review 13
  • preprint 10
  • book-chapter 7

Condition tags

  • endometriosis 201
  • adenomyosis 54
  • endometrioma 38
  • dysmenorrhea 28
  • infertility 24
  • chronic_pelvic_pain 11
  • dyspareunia 5
  • bowel_endometriosis 4
  • bladder_endometriosis 3
  • mesh:D004716 3
article 2005
Human Reproduction ·doi:10.1093/humrep/dei233

BACKGROUND: Adiponectin is a pleiotropic cytokine originally discovered as an adipocyte-specific gene product. Serum adiponectin concentrations have been reported to be low in women with endometrial cancer, breast cancer and uterine leiomyo…

article 2004
Human Reproduction ·doi:10.1093/humrep/deh412

BACKGROUND: Failure of apoptosis of refluxed endometrial cells within the peritoneal cavity is a possible etiologic factor for development of endometriosis. Osteoprotegerin (OPG) is a survival factor that exerts its effect by binding to tum…

article 2004
·doi:10.1016/j.fertnstert.2004.07.412
article 2004
·doi:10.2492/jsir.24.629

Given the current theory of inflammatory changes being involved in the progression of endometriosis, MAPKs might be at play as pivotal intracellular signal transducers in endometriotic cells and thus have a pathophysiological role in the di…

article 2004
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.2004.00231.x

PROBLEM: Endometriosis accompanies local inflammatory reactions in the peritoneal cavity. We examined the phosphorylation of mitogen-activated protein kinases (MAPKs), i.e. extracellular signal-regulated kinase (ERK), p38 MAPK (p38) and c-J…

article 2004
·doi:10.1016/j.fertnstert.2004.07.426
other 2003
Human Reproduction ·doi:10.1093/humrep/deg243

BACKGROUND: To evaluate the usefulness of transvaginal and transrectal ultrasonography for diagnosis and management of deeply infiltrating rectosigmoid endometriosis. METHODS: A series of six patients (aged 32-39 years) with rectosigmoid e…

article 2003
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1034/j.1600-0897.2003.00037.x

PROBLEM: To assess whether interferon-gamma-induced protein-10 (IP-10), a chemokine that has antiangiogenic activities, may be involved in the pathogenesis of endometriosis. METHOD OF STUDY: A total of 120 patients undergoing laparoscopy fo…

article 2003
International journal of oncology

Using a cDNA microarray consisting of 23,040 genes, we analyzed gene-expression profiles of ovarian endometrial cysts from 23 patients in order to identify genes involved in endometriosis. By comparing expression patterns between endometrio…

article 2002
·doi:10.1016/s0015-0282(02)04100-6
article 2002
·doi:10.1016/s0015-0282(01)03104-1
article 2002
Gynecologic and obstetric investigation ·doi:10.1159/000066290

To address the contrasting findings regarding how pain is related to endometriosis, the relationship between pain and stage of endometriosis was dissected differently by the chief complaint to eliminate selection biases. A total of 1,092 wo…

article 2002
·doi:10.1016/s0015-0282(01)03120-x
review 2002
Gynecologic and obstetric investigation ·doi:10.1159/000049422

Endometriosis is assumed to be one of the causative factors of infertility, although the mechanism remains to be elucidated. Mechanical factors distorting the pelvic anatomy and/or changes in the biochemical and cellular environment in the …

article 2001
Nihon rinsho. Japanese journal of clinical medicine
article 2001
Nihon rinsho. Japanese journal of clinical medicine
article 2001
Nihon rinsho. Japanese journal of clinical medicine
article 2001
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/j.1447-0756.2001.tb01255.x

Bowel endometriosis manifesting with ileus is difficult to diagnose, often requiring laparotomy for diagnosis and treatment. We report here a case of ileo-cecal endometriosis causing bowel obstruction. A diagnosis of intestinal endometriosi…

article 2000
The Journal of reproductive medicine

OBJECTIVE: To examine how preexisting tubal adhesions and endometriosis affect pregnancy outcome after laparoscopic treatment in infertile women with no apparent causes of infertility other than tubal factors. STUDY DESIGN: Pregnancy outcom…

article 2000
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.8755-8920.2000.440407.x

PROBLEM: In the quest for possible involvement of stem cell factor (SCF), a cytokine known to have multiple effects, in the pathogenesis of endometriosis, we evaluated concentrations of SCF in peritoneal fluid (PF) of women with or without …

article 1999
Endocrine journal ·doi:10.1507/endocrj.46.765

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) has been suggested as a possible etiologic factor for endometriosis, a condition in which endometrium-like tissues are present outside the uterus. The prevailing view pertaining to the origin of en…

article 1999
Human Reproduction ·doi:10.1093/humrep/14.6.1611

The concentrations of hepatocyte growth factor (HGF) in peritoneal fluid (PF) from women with endometriosis (n = 36) and without endometriosis (n = 40) were measured. All of the PF samples examined contained detectable concentrations of HGF…

article 1999
Human Reproduction ·doi:10.1093/humrep/14.10.2661

Vaginal agenesis combined with a functional uterus is a rare condition in which treatment modalities that preserve reproductive function are controversial. A 21 year old female presented with congenital vaginal agenesis combined with cervic…

article 1995
·doi:10.1093/oxfordjournals.humrep.a136083

Decidualized tissues are characterized by the intensive outgrowth of the microvasculature. Several angiogenic factors are assumed to be involved during the drastic change in the vasculature occurring in the process of decidualization. We ex…

article 1995
·doi:10.1093/molehr/1.2.69

Decidualized tissues are characterized by the intensive outgrowth of the microvasculature. Several angiogenic factors are assumed to be involved during the drastic change in the vasculature occurring in the process of decidualization. We ex…