Contraceptive properties of Danazol.

In: PubMed · 1976 · vol. 17(2) , pp. 98–101 · W2473442781
article OA: closed CC0 ⤵ 23 in-corpus citations
View on OpenAlex
AI-generated summary by claude@2026-06, 2026-06-08

Danazol administered daily to 30 volunteers at doses of 50, 100, or 200 mg prevented pregnancy and consistently inhibited ovulation at 200 mg, with minor side effects and rapid return of menstruation.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

The contraceptive properties of Danazol a steroid derivative of eth isterone were investigated in 30 volunteers. The drug was administered for 90 days in daily doses of either 50 100 or 200 mg. There were no pregnancies. Consistent inhibition of ovulation was obtained with the 200 mg dose only. An imbalance in hypothalamic-pituitary-ovarian activity was not observed. Side effects were minor and relatively infrequent. Regular menstruation was rapdily restored and 3 patients conceived within 3-4 months after cessation of treatment. Further studies of the 100-200 mg regimes are warranted.

My notes (saved in your browser only)

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (23)

Source provenance

openalex
last seen: 2026-05-10T10:07:21.701259+00:00
License: CC0 · commercial use OK