Endometriosis-related chronic pelvic pain: A mini review on pathophysiology and impact on mental health

Thomas Vrekoussis, Vassiliki Siafaka, Alexandra Tsitou, Orestis Tsonis, Iordanis Navrozoglou, Antonis Makrigiannakis, Minas Paschopoulos
In: Journal of Endometriosis and Pelvic Pain Disorders · 2020 · vol. 12(1) , pp. 35–40 · doi:10.1177/2284026519895829 · W2999911799
review OA: closed CC0 ⤵ 4 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This review outlines the pathophysiology of endometriosis-related chronic pelvic pain as chronic stress on the central nervous system due to inflammation, impacting mental health and quality of life.

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Abstract

Endometriosis-related chronic pelvic pain is a major component of the disease that affects quality of life in women of reproductive age suffering from endometriosis. The present review summarizes current evidence upon pathophysiology and its impact on mental health. It seems that endometriosis-related chronic pelvic pain is the result of chronic stress on the central nervous system as a consequence of chronic pelvic inflammation. Mental health issues may rise as a result of central nervous system derangement and further aggravate pain perception and therefore quality of life. Further properly designed studies are needed in order to elucidate the connection between mental disorders and endometriosis-related chronic pelvic pain.

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Condition tags

endometriosischronic_pelvic_pain

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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last seen: 2026-06-10T17:14:06.276822+00:00
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