Factors Associated with Severity of Irritable Bowel Syndrome Symptoms in Patients with Endometriosis

Lee CE, Caroline E. Lee, Paul J. Yong, Christina Williams, Williams C, Catherine Allaire, Allaire C
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC · 2017 · vol. 40(2) , pp. 158–164 · doi:10.1016/j.jogc.2017.06.025 · PMID:28870721 · W2751782165
Observational OA: closed CC0 ⤵ 22 in-corpus citations
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This study identified lower-stage endometriosis, mood disorders, physical tenderness, sexual assault history, and sleep disturbance as factors associated with increased irritable bowel syndrome symptom severity in endometriosis patients.

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Abstract

OBJECTIVE: This study sought to examine factors associated with severity of irritable bowel syndrome (IBS) by using the Birmingham IBS symptom scale in patients presenting with endometriosis to a tertiary referral centre. METHODS: A prospective research cohort of patients presenting to a tertiary referral centre for endometriosis was evaluated for the presence and severity of IBS between December 2013 and April 2015. Patients with endometriosis had a diagnosis of IBS by using the Rome III criteria and were evaluated for severity of IBS symptoms by using the Birmingham IBS symptom scale. Multifactorial variables, including stage of endometriosis at the time of previous surgery, clinical examination findings, mood disorder questionnaire scores, and lifestyle factors, were evaluated using the t test and Spearman rank correlation test. RESULTS: A total of 194 of 373 (52%) women with confirmed endometriosis had a diagnosis of IBS. Factors associated with severity of IBS symptoms in patients with endometriosis included lower-stage endometriosis (P = 0.004), presence of mood disorders (P <0.001), tenderness on physical examination (P ≤ 0.001), a history of sexual assault (P ≤ 0.02), and presence of sleep disturbance (P ≤ 0.01). Evaluation of the subscales of the Birmingham IBS symptom scale revealed a strong association between the previously identified factors and the pain subscale. CONCLUSION: Using the Birmingham IBS symptom scale, our study revealed more severe IBS symptoms in patients with lower-stage endometriosis and identified other variables highly associated with severity of IBS. Continued research is required to characterize further the clinical importance of IBS symptoms in patients with endometriosis-associated pelvic pain.

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Condition tags

endometriosischronic_pelvic_painirritable_bowel_syndrome

MeSH descriptors

Endometriosis Endometriosis Irritable Bowel Syndrome Irritable Bowel Syndrome Adult Adult Diet Diet Endometriosis Endometriosis Female Female Humans Humans Irritable Bowel Syndrome Irritable Bowel Syndrome Mood Disorders Mood Disorders Pelvic Pain Pelvic Pain

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (37)

Cited by (24)

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