Primary umbilical endometriosis (PUE)

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This paper describes ten cases of primary umbilical endometriosis, a rare condition presenting with cyclic umbilical changes, and highlights diagnostic challenges leading to initial gastro-surgeon referrals before confirmation by imaging and histology.

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Abstract

Primary endometriosis of the umbilicus, Villars nodule, rarely occurs. It is characterized by a discolored change in the umbilicus which manifests itself with cyclic menstrual-related symptoms such as pain, swelling and bleeding. Often the diagnosis is based on objective findings, but imaging and histology predicts and verify the diagnosis. Radical excision is performed with good results. We present ten cases with primary umbilical endometriosis and present the referral pattern dominated by primary referral to the gastro-surgeon reflecting difficulties in finding the right diagnosis.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Umbilicus Adult Adult Endometriosis Endometriosis Endometriosis Female Female Humans Humans Umbilicus Umbilicus Young Adult Young Adult

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (14)

Cited by (38)

Source provenance

europepmc
last seen: 2026-10-14T06:08:39.101224+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:18:11.460223+00:00
License: CC0 · commercial use OK