Impact of Endometriosis on Fatigue and Productivity Impairment in a Cross-Sectional Survey of Canadian Women

Ahmed M. Soliman, Yasmine Rahal, Rahal Y, Catherine Robert, Robert C, Defoy I, Isabelle Defoy, Nisbet P, Paul Nisbet, Nicholas Leyland, Leyland N, Singh S, Sukhbir Singh, Sukhbir S. Singh
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC · 2020 · vol. 43(1) , pp. 10–18 · doi:10.1016/j.jogc.2020.06.022 · PMID:32978082 · W3042364991
Observational OA: bronze CC0 ⤵ 30 in-corpus citations
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This cross-sectional survey examined the impact of endometriosis on fatigue levels and productivity impairment among Canadian women.

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Abstract

OBJECTIVE: To evaluate fatigue burden and productivity impairments in Canadian women with a self-reported diagnosis of endometriosis (DxE). METHODS: From December 2018 to January 2019, Canadian women aged 18-49 years completed an online survey assessing fatigue via the Patient-Reported Outcomes Measurement Information System (PROMIS) Fatigue Short Form 6a questionnaire. Fatigue T-scores were compared between women with and without a DxE, by age and endometriosis symptom severity, using t tests. Women with a DxE completed the Work Productivity and Activity Impairment - Specific Health Problem (WPAI-SHP) questionnaire. The effects of age and hallmark endometriosis symptoms on productivity impairments were assessed via analysis of variance. RESULTS: Survey data included 2004 women with and 26 528 women without a DxE. Mean fatigue T-scores were 58.5 ± 10.1 in women with a DxE and 59.2 ± 10.1 in women with hallmark endometriosis symptoms (i.e., menstrual or non-menstrual pelvic pain/cramping, dyspareunia) versus 55.2 ± 9.4 in women without a DxE (both P < 0.001). Women with moderate or severe endometriosis symptoms had a mean T-score of 61.2 ± 9.4 versus 55.9 ± 10.1 for women with mild symptoms (P < 0.001). Women with moderate or severe hallmark endometriosis symptoms had mean T-scores of 59.6-62.9 versus 57.0-58.2 for women with mild or no symptoms (all comparisons P < 0.01). Women with a DxE reported 17.1% of work time missed, 41.8% impaired work ability, 46.5% overall work impairment, and 41.4% activity impairment per the WPAI-SHP. Women with a DxE aged 30-34 and 35-39 years consistently experienced the greatest effects of fatigue and productivity impairments. CONCLUSIONS: Canadian women with a DxE experience a substantial fatigue burden and significant productivity impairments.

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Absenteeism Absenteeism Efficiency Efficiency Endometriosis Fatigue Presenteeism Presenteeism Quality of Life Adolescent Adolescent Adult Adult Canada Canada Canada Cost of Illness Cost of Illness Cross-Sectional Studies Cross-Sectional Studies

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