Tumor Necrosis Factor in Plasma and Peritoneal Fluid of Women with and without Endometriosis

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Abstract

To determine whether in vivo levels of tumor necrosis factor a in plasma and peritoneal fluid differ in infertile subjects with and without endometriosis, peripheral blood and peritoneal fluid samples were collected in 94 women undergoing laparoscopy for infertility. Quantitative determinations of tumor necrosis factor a were performed by an enzyme immunoassay test. Tumor necrosis factor a levels were below the detection limit (10 pg/ml) in plasma and peritoneal fluid of 42 (91%) and 30 (90%) patients with endometriosis and 40 (83%) and 31 (91%) subjects without the disease, respectively. In our series, plasma and tumor necrosis factor a levels were not different in infertile women with and without endometriosis.

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Condition tags

endometriosisinfertility

MeSH descriptors

Ascitic Fluid Endometriosis Genital Neoplasms, Female Infertility, Female Tumor Necrosis Factor-alpha Adult Ascitic Fluid Endometriosis Female Genital Neoplasms, Female Humans Immunoenzyme Techniques Infertility, Female Tumor Necrosis Factor-alpha

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europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:11:44.647872+00:00
License: CC0 · commercial use OK