Parametrial and rectovaginal adenocarcinoma arising from endometriosis

U Ulrich, Ulrich U, K Rhiem, Kerstin Rhiem, Monique Kaminski, Kaminski M, M Kaminski, Wardelmann E, Eva Wardelmann, E Wardelmann, Daniela Trog, Trog D, D Trog, Valter M, Markus M. Valter, M Valter, Richter ON, O N Richter, O. Richter
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2005 · vol. 15(6) , pp. 1206–1209 · doi:10.1111/j.1525-1438.2005.00184.x · PMID:16343215 · W2067457031
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⚙ AI-generated summary by claude@2026-06, 2026-06-28 ⓘ

This paper describes two cases of adenocarcinoma originating from endometriosis in the parametrial and rectovaginal regions.

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Abstract

Malignant extragonadal tumors arising from endometriosis are rare. We report on two cases. A 41-year-old gravida 1, para 1 (G1P1), with adenocarcinoma of the right parametrium arising from endometriosis and a 51-year-old G1P1 with endometriosis-associated rectovaginal adenocarcinoma were treated. Treatment included radical surgery plus radiation therapy. While the former patient was doing well 2 years after the primary diagnosis, the latter suffered a local pelvic recurrence 2 years later. Although there are no randomized controlled studies, radical surgery followed by radiation therapy seems generally to be the treatment of choice. The analysis of PTEN in various forms of endometriosis and its malignant transformation may help in understanding the early steps of tumorigenesis.

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma Endometriosis Pelvic Neoplasms Rectal Neoplasms Vaginal Neoplasms Adenocarcinoma Adenocarcinoma Adenocarcinoma Adult Antineoplastic Agents Antineoplastic Agents Carboplatin Carboplatin Cell Transformation, Neoplastic Colectomy Endometriosis Endometriosis Female Gynecologic Surgical Procedures Humans

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (13)

Cited by (40)

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