Clinical significance of adenomyosis
Observational
OA: closed
CC0
⤵ 27 in-corpus citations
AI-generated summary
This study found adenomyosis to be a benign, often underdiagnosed condition linked to pregnancy and delivery, with unclear symptoms and little clinical significance in parous women over 40.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
During the years 1968--1972, 903 patients with endometriosis were operated on in the Turku University Central Hospital, of whom 136 were found to have adenomyosis (endometriosis interna). The diagnosis of adenomyosis was usually made post-operatively from following examination of uterus; only 15% were suspected to have adenomyosis preoperatively. 24% of the patients also had external endometriosis. The symptoms and the clinical finding were analysed, but the results were quite unclear and were often easier to explain in terms of other simultaneous diseases or of menopausal disturbances. Adenomyosis, unlike external endometriosis, did not cause sterility. A study of the aetiology showed that only 6% had had no pregnancies. Adenomyosis is a benign disease with little clinical significance. Its symptoms are unclear and it is usually underdiagnosed, but it may actually appear in more than 50% of parous women over the age of 40. In this study, the only aetiology of adenomyosis appeared to be pregnancy and/or delivery. Finally it is suggested that adenomyosis may be a more or less physiological finding in parous women, with the highest frequency of occurrence in the female population over the age 30 years when childbearing is generally over.
My notes (saved in your browser only)
Condition tags
MeSH descriptors
Citation neighborhood (2-hop)
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]
Cited by (26)
- [Epidemiological and anatomopathological profile of endometriosis in Dakar: retrospective study over a period of 20 years] 2023
- Epidemiology of Adenomyosis 2020
- No. 164-Consensus Guidelines for the Management of Chronic Pelvic Pain 2018
- No 164 - Directive clinique de consensus pour la prise en charge de la douleur pelvienne chronique 2018
- Down-regulation of tumor suppressor PDCD4 expression in endometrium of adenomyosis patients 2016
- [Uterine adenomyosis, clinical and therapeutic study: about 87 cases] 2015
- Distinct types of uterine adenomyosis based on laparoscopic and histopathologic criteria 2014
- Constitutive and tumor necrosis factor-α-induced activation of nuclear factor-κB in adenomyosis and its inhibition by andrographolide 2013
- Adenomyosis: Pathologies associated in a set of patients underwent hysterectomy 2012
- Elevated immunoreactivity to tissue factor and its association with dysmenorrhea severity and the amount of menses in adenomyosis 2010
- Evaluation Of Chronic Pelvic Pain In Women 2010
- Immunoreactivity of oxytocin receptor and transient receptor potential vanilloid type 1 and its correlation with dysmenorrhea in adenomyosis 2010
- Adenomyosis uteri: an update 2009
- Uterine artery embolization for the treatment of adenomyosis 2008
- Hormone-dependent gynaecological disorders: a pathophysiological perspective for appropriate treatment 2007
- Laparoscopic excision of uterine adenomyomas 2007
- The symptomatology of adenomyosis 2006
- Adenomyosis: what is the impact on fertility? 2005
- Consensus guidelines for the management of chronic pelvic pain 2005
- Adenomyosis 2003
- Medium-term follow-up of women with menorrhagia treated by rollerball endometrial ablation 2000
- Is adenomyosis an immune disease? 1998
- Pathophysiology of adenomyosis 1998
- Myometrial biopsy in the diagnosis of adenomyosis uteri 1993
- Adenomyosis: current perspectives 1989
- Non-specificity of symptoms related to adenomyosis. A prospective comparative survey 1984
Source provenance
- europepmc
- last seen: 2026-10-17T06:09:56.316927+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:58:37.372514+00:00
License: CC0
· commercial use OK