Myometrial biopsy in the diagnosis of adenomyosis uteri

L. Popp, L W Popp, Popp LW, Schwiedessen JP, Jens P. Schwiedessen, J P Schwiedessen, R Gaetje, Gaetje R
American Journal of Obstetrics and Gynecology · 1993 · vol. 169(3) , pp. 546–549 · doi:10.1016/0002-9378(93)90617-r · PMID:8372859 · W2084213406
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This study investigated the utility of myometrial biopsy in diagnosing adenomyosis uteri by comparing histopathological findings.

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Abstract

ObjectiveAutomatic cutting needle sampling was used for diagnosis of adenomyosis uteri. The purpose of this study was the establishment of myometrial biopsy as a clinically applicable method.Study designSensitivity and specificity of myometrial biopsy in diagnosis of uterine adenomyosis was estimated by examining 680 biopsy specimens from 68 surgically removed uteri. In 34 patients with clinical symptoms of adenomyosis uteri 70 myometrial biopsies were performed during laparoscopy, and vaginal ultrasonographically guided myometrial biopsy was performed in six patients (14 specimens) without complications. Prevention of myometrial bleeding was achieved by prophylactic injection of ornipressin into the biopsy cannula.ResultsThe sensitivity of a single myometrial sample for diagnosing adenomyosis uteri ranged from 8% to 18.7%; specificity was 100%.ConclusionOur results may encourage further investigation on the clinical use of myometrial biopsy.

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Condition tags

endometriosisadenomyosis

MeSH descriptors

Biopsy, Needle Endometriosis Myometrium Uterine Neoplasms Biopsy, Needle Biopsy, Needle Blood Loss, Surgical Blood Loss, Surgical Endometriosis Evaluation Studies as Topic Female Humans Myometrium Ornipressin Ornipressin Sensitivity and Specificity Uterine Neoplasms

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (18)

Cited by (40)

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