Myometrial biopsy in the diagnosis of adenomyosis uteri

L. Popp, L W Popp, Popp LW, Schwiedessen JP, Jens P. Schwiedessen, J P Schwiedessen, R Gaetje, Gaetje R
American journal of obstetrics and gynecology · 1993 · vol. 169(3) , pp. 546–549 · doi:10.1016/0002-9378(93)90617-r · PMID:8372859 · W2084213406
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This study investigated the utility of myometrial biopsy in diagnosing adenomyosis uteri by comparing histopathological findings.

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Abstract

OBJECTIVE: Automatic cutting needle sampling was used for diagnosis of adenomyosis uteri. The purpose of this study was the establishment of myometrial biopsy as a clinically applicable method. STUDY DESIGN: Sensitivity and specificity of myometrial biopsy in diagnosis of uterine adenomyosis was estimated by examining 680 biopsy specimens from 68 surgically removed uteri. In 34 patients with clinical symptoms of adenomyosis uteri 70 myometrial biopsies were performed during laparoscopy, and vaginal ultrasonographically guided myometrial biopsy was performed in six patients (14 specimens) without complications. Prevention of myometrial bleeding was achieved by prophylactic injection of ornipressin into the biopsy cannula. RESULTS: The sensitivity of a single myometrial sample for diagnosing adenomyosis uteri ranged from 8% to 18.7%; specificity was 100%. CONCLUSION: Our results may encourage further investigation on the clinical use of myometrial biopsy.

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Condition tags

endometriosisadenomyosis

MeSH descriptors

Biopsy, Needle Endometriosis Myometrium Uterine Neoplasms Biopsy, Needle Biopsy, Needle Biopsy, Needle Blood Loss, Surgical Blood Loss, Surgical Blood Loss, Surgical Endometriosis Endometriosis Evaluation Studies as Topic Evaluation Studies as Topic Female Female Humans Humans Myometrium Myometrium

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (18)

Cited by (40)

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