GnRH agonists and add‐back therapy: is there a perfect combination?
review
OA: closed
CC0
⤵ 21 in-corpus citations
Limited metadata. Only one source feed has indexed
this record so far — no abstract, full text, or open-access copy is
available through Endo Lab. The
publisher's page (linked below)
is the canonical location for the actual content. If you have institutional
access, use "Find at my library".
AI-generated summary
This review explores the optimal combination of GnRH agonists and add-back therapy for managing endometriosis, discussing current evidence and future directions.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
My notes (saved in your browser only)
Condition tags
MeSH descriptors
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
References (100)
- A Comparison of the Skeletal Effects of Goserelin and Danazol in Premenopausal Women with Endometriosis via openalex
- Add-back therapy in the treatment of endometriosis: the North American experience. via openalex
- An alternative to hysterectomy? GnRH analogue combined with hormone replacement therapy via openalex
- A randomized double blind placebo controlled trial of the effects on bone metabolism of the combination of nafarelin acetate and norethisterone via openalex
- Bone mass in endometriosis patients treated with GnRH agonist implant or danazol. via openalex
- Effectiveness of tibolone on hypoestrogenic symptoms induced by goserelin treatment in patients with endometriosis via openalex
- Effects of nafarelin versus danazol on lipids and calcium metabolism via openalex
- Endocrine effects of GnRH analogue with low‐dose hormone replacement therapy in women with endometriosis via openalex
- Gonadotropin-Releasing Hormone (GnRH) Agonists in the Management of Endometriosis: A Review via openalex
- Human uterine endometrium and endometriotic tissue transplanted into nude mice. Morphologic effects of various steroid hormones. via openalex
- Is It Possible to Prevent Bone Loss in Young Women Treated with Luteinizing Hormone-Releasing Hormone Agonists? via openalex
- LH-RH agonist (Buserelin): treatment of endometriosis via openalex
- Long‐acting gonadotrophin releasing hormone agonist implant causes variable duration of suppression of ovarian steroid and inhibin secretion via openalex
- Long-term suppression of ovarian function by a luteinizing-hormone releasing hormone agonist implant in patients with endometriosis via openalex
- Lupron depot (leuprolide acetate for depot suspension) in the treatment of endometriosis: a randomized, placebo-controlled, double-blind study via openalex
- Medroxyprogesterone acetate supplementation diminishes the hypoestrogenic side effects of gonadotropin-releasing hormone agonist without changing its efficacy in endometriosis via openalex
- Metabolic changes during medical treatment of endometriosis: Nafarelin acetate versus danazol via openalex
- Multiple gestation following gonadotrophin releasing hormone therapy for the treatment of minimal endometriosis via openalex
- Placebo-controlled comparison of danazol and high-dose medroxyprogesterone acetate in the treatment of endometriosis via openalex
- Prevention of follicular maturation in endometriosis by subcutaneous infusion of luteinizing hormone-releasing hormone agonist started in the luteal phase via openalex
- Prolonged gonadotropin-releasing hormone agonist treatment of symptomatic endometriosis: the role of cyclic sodium etidronate and low-dose norethindrone “add-back” therapy via openalex
- Reduction of vasomotor symptoms and bone mineral density loss with combined norethindrone and long-acting gonadotropin-releasing hormone agonist therapy of symptomatic endometriosis: a prospective randomized trial via openalex
- Reduction of vasomotor symptoms and bone mineral density loss with combined norethindrone and long-acting gonadotropin-releasing hormone agonist therapy of symptomatic endometriosis: a prospective randomized trial. via openalex
- Regulation of estrogen/progestogen receptors in the endometrium. via openalex
- Severe endometriosis treated with gonadotrophin releasing hormone agonist and continuous combined hormone replacement therapy via openalex
- Should add-back therapy for endometriosis be deferred for optimal results? via openalex
- Spontaneous reversibility of bone loss induced by gonadotropin-releasing hormone analog treatment via openalex
- Spontaneous reversibility of bone loss induced by gonadotropin-releasing hormone analog treatment. via openalex
- The effect of add-back treatment with tibolone (Livial) on patients treated with the gonadotropin-releasing hormone agonist triptorelin (Decapeptyl) via openalex
- The effects of combining norethindrone with a gonadotropin-releasing hormone agonist in the treatment of symptomatic endometriosis via openalex
- The effects of combining norethindrone with a gonadotropin‐releasing hormone agonist in the treatment of symptomatic endometriosis via openalex
- The pathogenesis and aetiology of endometriosis via openalex
- The use of newer progestins in the treatment of endometriosis via openalex
- Treatment of endometriosis with a long-acting gonadotropin-releasing hormone agonist. via openalex
- Treatment of endometriosis with a long-acting gonadotropin-releasing hormone agonist plus medroxyprogesterone acetate. via openalex
- Zoladex (goserelin acetate implant) in the treatment of endometriosis: a randomized comparison with danazol. The Zoladex Endometriosis Study Group. via openalex
- Zoladex versus Danazol in the Treatment of Pelvic Endometriosis: Effects on Plasma Lipid Risk Factors via openalex
- W2003292227 via openalex
- W2003845868 via openalex
- W2004383762 via openalex
- W2005804463 via openalex
- W2006732320 via openalex
- W2007635884 via openalex
- W2009881284 via openalex
- W2013079995 via openalex
- W2014486464 via openalex
- W2018728968 via openalex
- W2022120014 via openalex
- W2024776674 via openalex
- W2024931543 via openalex
- W2029564100 via openalex
- W2033095316 via openalex
- W2033323530 via openalex
- W2034496535 via openalex
- W2036125852 via openalex
- W2037690190 via openalex
- W2037760875 via openalex
- W2040352396 via openalex
- W2040523806 via openalex
- W2042949087 via openalex
- W2043018121 via openalex
- W2044134855 via openalex
- W2044970382 via openalex
- W2046683546 via openalex
- W2046983302 via openalex
- W2047366838 via openalex
- W2049987798 via openalex
- W2053593143 via openalex
- W2054391347 via openalex
- W2062982521 via openalex
- W2064170995 via openalex
- W2068011646 via openalex
- W2073640827 via openalex
- W2074154683 via openalex
- W2078629144 via openalex
- W2084296217 via openalex
- W2086174901 via openalex
- W2086872954 via openalex
- W2090069024 via openalex
- W2091159054 via openalex
- W2097113048 via openalex
- W2110106415 via openalex
- W2114624401 via openalex
- W2115941653 via openalex
- W2122080406 via openalex
- W2122745505 via openalex
- W2129449855 via openalex
- W2144238512 via openalex
- W2151649765 via openalex
- W2153895111 via openalex
- W2157317148 via openalex
- W2159073955 via openalex
- W2162008876 via openalex
- W2231621418 via openalex
- W2264069562 via openalex
- W2277353524 via openalex
- W2284731191 via openalex
- W2287197347 via openalex
- W2287757320 via openalex
- W2292796156 via openalex
Cited by (21)
- Dienogest-The Millennium Molecule!! 2018
- Dienogest - The Millennium Molecule!! 2017
- Raloxifene Administration in Women Treated with Long Term Gonadotropin-releasing Hormone Agonist for Severe Endometriosis: Effects on Bone Mineral Density 2016
- Treatment of Endometriosis with the GnRHa Deslorelin and Add-Back Estradiol and Supplementary Testosterone 2015
- Medical Treatment of Chronic Pelvic Pain 2014
- Serum levels of estradiol and follicle stimulating hormone,and vasomotor symptoms in Thai women receivingGnRH analogue before laparoscopic enucleationof endometriotic cysts 2012
- Hormonal strategy for the primary or secondary treatment of endometriosis 2012
- Gonadotropin releasing hormone agonists: Expanding vistas 2011
- Endometriosis 2009
- Traitements des localisations urologiques de l'endométriose 2009
- GnRH-Analoga und Add-back-Verfahren 2008
- Expression und Regulation von Enzymen des Östrogenmetabolismus in humanen Endometriumläsionen kultiviert in der Nacktmaus 2007
- Benign Gynecological Diseases and SERMs 2006
- Treatment with leuprolide acetate and hormonal add-back for up to 10 years in stage IV endometriosis patients with chronic pelvic pain 2006
- GnRH analogs for the treatment of symptomatic uterine leiomyomas 2005
- Gonadotropin-releasing hormone agonist with or without raloxifene: Effects on cognition, mood, and quality of life 2004
- One year comparison between two add-back therapies in patients treated with a GnRH agonist for symptomatic endometriosis: a randomized double-blind trial 2004
- Prevention of bone loss and hypoestrogenic symptoms by estrogen and interrupted progestogen add-back in long-term GnRH-agonist down-regulated patients with endometriosis and premenstrual syndrome 2002
- Bone metabolism in postmenopausal women who were treated with a gonadotropin-releasing hormone agonist and tibolone 2002
- Gonadotropin-releasing hormone agonist plus “add-back” hormone replacement therapy for treatment of endometriosis: a prospective, randomized, placebo-controlled, double-blind trial 2000
- Current and Potential Application of GnRH Agonists in Gynecologic Practice 2000
Source provenance
- europepmc
- last seen: 2026-09-13T09:25:22.628771+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:10:40.754221+00:00
License: CC0
· commercial use OK