Treatment of Menorrhagia
This chapter discusses menorrhagia as excessive menstrual blood loss, distinguishing between clinical diagnosis and objective research measurements of blood loss.
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This chapter reviews how menorrhagia is defined clinically versus in objective research measurements, noting that excessive bleeding is commonly reported by patients but correlates poorly with measured menstrual blood loss thresholds such as >80 ml per cycle. It discusses the difficulty of objective confirmation of heavy bleeding in routine practice and therefore contrasts broader clinical diagnosis with narrower research definitions. The chapter also surveys related evidence and therapeutic approaches that target uterine prostaglandin pathways and other mechanisms, reflecting the role of prostaglandins in menstrual bleeding. A major limitation is that the clinical and research definitions are not uniform, complicating interpretation and comparison across studies, particularly when patient-reported heaviness is used. Relevance to endometriosis: the chapter cites prostanoid concentration in women with endometriosis and includes background on prostaglandins and endometrial/endometriosis biology, though it is centrally about treatment and measurement issues in menorrhagia rather than endometriosis itself.
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References (69)
- 11 Treatment of menorrhagia via openalex
- A comparison of flurbiprofen, tranexamic acid, and a levonorgestrel-releasing intrauterine contraceptive device in the treatment of idiopathic menorrhagia via openalex
- Control of menorrhagia by the cyclo‐oxygenase inhibitors naproxen sodium and mefenamic acid via openalex
- Efficacy of mefenamic acid in patients with a complaint of menorrhagia. via openalex
- Gestrinone in the treatment of menorrhagia via openalex
- Laser photovaporization of endometrium for the treatment of menorrhagia via openalex
- Levonorgestrel‐releasing intrauterine device in the treatment of menorrhagia via openalex
- Management of Cyclical Menorrhagia with Prostaglandin Synthetase Inhibitor via openalex
- Measured menstrual blood loss in women with menorrhagia associated with pelvic disease or coagulation disorder. via openalex
- Primary and myoma‐associated menorrhagia: role of prostaglandins and effects of ibuprofen via openalex
- Prostaglandin biosynthesis inhibitors and endometriosis via openalex
- Randomized Trial of 2 Hormonal and 2 Prostaglandin‐inhibiting Agents in Women with a Complaint of Menorrhagia via openalex
- REDUCTION OF MENSTRUAL BLOOD LOSS BY DANAZOL IN UNEXPLAINED MENORRHAGIA: LACK OF EFFECT OF PLACEBO via openalex
- REDUCTION OF MENSTRUAL BLOOD-LOSS BY PROSTAGLANDIN-SYNTHETASE INHIBITORS via openalex
- Studies in Menorrhagia: (a) Mefenamic Acid, (b) Endometrial Prostaglandin Concentrations via openalex
- The endometrium and endometriosis via openalex
- The potential for the use of GnRH agonists for treatment of dysfunctional uterine bleeding via openalex
- The Use of the Prostaglandin Synthetase Inhibitor Mefenamic Acid in the Treatment of Menorrhagia via openalex
- Treatment of menorrhagia with intrauterine release of progesterone via openalex
- Use of a super active luteinizing hormone releasing hormone (LHRH) agonist in the treatment of menorrhagia via openalex
- W2000210781 via openalex
- W2006005007 via openalex
- W2012165536 via openalex
- W2019664919 via openalex
- W2024180604 via openalex
- W2032853276 via openalex
- W2044636737 via openalex
- W2056895439 via openalex
- W2059349398 via openalex
- W2076652047 via openalex
- W2081455781 via openalex
- W2083517870 via openalex
- W2085847265 via openalex
- W2086126831 via openalex
- W2088804413 via openalex
- W2099229592 via openalex
- W2137468059 via openalex
- W2154327088 via openalex
- W2253945284 via openalex
- W2262180574 via openalex
- W2396072047 via openalex
- W2405503781 via openalex
- W2472824961 via openalex
- W2591340754 via openalex
- W2610909957 via openalex
- W4241547623 via openalex
- W4285719527 via openalex
- W4290303883 via openalex
- W3470488 via openalex
- W6720661875 via openalex
- W51706072 via openalex
- W63062164 via openalex
- W100781816 via openalex
- W161606555 via openalex
- W161903888 via openalex
- W191591924 via openalex
- W653439884 via openalex
- W1497675019 via openalex
- W1538894163 via openalex
- W1540083309 via openalex
- W1783602832 via openalex
- W1963909284 via openalex
- W1964478303 via openalex
- W1967196000 via openalex
- W1967882448 via openalex
- W1978050262 via openalex
- W1978711334 via openalex
- W1983060435 via openalex
- W1998687386 via openalex
Cited by (8)
- The Clinical Relevance of Disturbances of Uterine Vascular Growth, Remodeling, and Repair 2001
- Vascular smooth muscle cell proliferation in arterioles of the human endometrium 1999
- Smooth muscle alpha actin and myosin heavy chain expression in the vascular smooth muscle cells surrounding human endometrial arterioles 1999
- Dysfunctional uterine bleeding. 1998
- Menstrual Changes During the Perimenopause 1997
- Dysfunctional uterine bleeding and dysmenorrhea 1997
- Vascular smooth muscle -actin distribution around endometrial arterioles during the menstrual cycle: increased expression during the perimenopause and lack of correlation with menorrhagia 1996
- 8 Prostaglandins, prostaglandin inhibitors and their roles in gynaecological disorders 1992
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- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00