Use of a super active luteinizing hormone releasing hormone (LHRH) agonist in the treatment of menorrhagia
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Intranasal administration of a super active LHRH agonist significantly reduced menorrhagia in four women, with blood loss returning to baseline after therapy cessation.
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Abstract
A luteinizing hormone releasing hormone agonist, D-Ser(But)6des Gly10-LHRH ethylamide, was administered intranasally to four women with unexplained ovulatory menorrhagia. Dramatic reductions in excessive menstrual blood losses were induced without significant side-effects, although the pattern of loss returned to pretreatment levels within 2 months of ceasing therapy.
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References (9)
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Cited by (16)
- Medical management of menstrual disorders 2004
- Benefits and Risks of Pharmacological Agents Used for the Treatment of Menorrhagia 2004
- Medical management of dysfunctional uterine bleeding 1999
- Assessment of medical treatments for menorrhagia 1994
- Gonadotropin releasing hormone agonist treatment for severe menorrhagia in patients with contraindications to surgery 1992
- A randomized double blind placebo controlled trial of the effects on bone metabolism of the combination of nafarelin acetate and norethisterone 1992
- Treatment of Menorrhagia 1992
- The potential for the use of GnRH agonists for treatment of dysfunctional uterine bleeding 1992
- Report on a conference on developments in the treatment of benign gynecological disorders 1992
- 8 Prostaglandins, prostaglandin inhibitors and their roles in gynaecological disorders 1992
- Gonadotropin Releasing Hormone Analogues in Gynaeocology 1990
- Management of menorrhagia. 1990
- 11 Treatment of menorrhagia 1989
- 10 LHRH analogues in the treatment of endometriosis—comparative results with other treatments 1988
- REVERSIBLE TRABECULAR BONE DENSITY LOSS FOLLOWING INDUCED HYPO‐OESTROGENISM WITH THE GnRH ANALOGUE BUSERELIN IN PREMENOPAUSAL WOMEN 1988
- Suppression of Follicular Maturation by Infusion of a Luteinizing Hormone-Releasing Hormone Agonist Starting during the Late Luteal Phase in the Stumptailed Macaque Monkey 1985
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noordeloos 2009062
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- last seen: 2026-06-10T17:14:06.276822+00:00
- scilite
- last seen: 2026-05-18T04:57:49.680383+00:00
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