Use of a superactive luteinizing hormone releasing hormone (LHRH) agonist in the treatment of menorrhagia
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⤵ 17 in-corpus citations
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Intranasal administration of a super active LHRH agonist significantly reduced menorrhagia in four women, with blood loss returning to baseline after therapy cessation.
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Abstract
A luteinizing hormone releasing hormone agonist, D-Ser(But)6des Gly10-LHRH ethylamide, was administered intranasally to four women with unexplained ovulatory menorrhagia. Dramatic reductions in excessive menstrual blood losses were induced without significant side-effects, although the pattern of loss returned to pretreatment levels within 2 months of ceasing therapy.
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References (9)
- Intranasal treatment with luteinising hormone releasing hormone agonist in women with endometriosis via openalex
- Reduction of menstrual blood loss by danazol in unexplained menorrhagia: lack of effect of placebo via openalex
- The use of danazol in the management of endometriosis. via openalex
- W2075790322 via openalex
- W2129737161 via openalex
- W2007840376 via openalex
- W4247840597 via openalex
- W2012521400 via openalex
- W2046432953 via openalex
Cited by (16)
- Medical management of menstrual disorders 2004
- Benefits and risks of pharmacological agents used for the treatment of menorrhagia 2004
- Medical management of dysfunctional uterine bleeding 1999
- Assessment of medical treatments for menorrhagia 1994
- Gonadotropin releasing hormone agonist treatment for severe menorrhagia in patients with contraindications to surgery 1992
- A randomized double blind placebo controlled trial of the effects on bone metabolism of the combination of nafarelin acetate and norethisterone 1992
- Treatment of Menorrhagia 1992
- The potential for the use of GnRH agonists for treatment of dysfunctional uterine bleeding 1992
- Report on a conference on developments in the treatment of benign gynecological disorders 1992
- Prostaglandins, prostaglandin inhibitors and their roles in gynaecological disorders 1992
- Gonadotropin releasing hormone analogues in gynaecology 1990
- Management of menorrhagia 1990
- Treatment of menorrhagia 1989
- LHRH analogues in the treatment of endometriosis--comparative results with other treatments 1988
- Reversible trabecular bone density loss following induced hypo-oestrogenism with the GnRH analogue buserelin in premenopausal women 1988
- Suppression of follicular maturation by infusion of a luteinizing hormone-releasing hormone agonist starting during the late luteal phase in the stumptailed macaque monkey 1985
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organisms 1
noordeloos 2009062
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- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:58:15.129929+00:00
- scilite
- last seen: 2026-05-18T04:57:49.680383+00:00
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