Spontaneous cutaneous umbilical endometriosis: report of a new case with immunohistochemical study and literature review
Review
OA: green
CC0
⤵ 60 in-corpus citations
AI-generated summary
This paper reports a case of spontaneous umbilical endometriosis, a rare condition where endometrial tissue grows on the skin, and reviews its clinical and pathological characteristics.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
Endometriosis (i.e., the presence of functional endometrial tissue outside the uterine cavity) may rarely affect the skin either spontaneously or secondary to abdomino-pelvic surgery. Spontaneous cutaneous endometriosis appears most commonly on the umbilicus (Villar nodule) and manifests with a red-brown nodule that characteristically shows cyclic variations (tenderness or bleeding) with the menstrual cycle. We present herein a new case of spontaneous cutaneous endometriosis of the umbilicus that was studied immunohistochemically and review the salient clinicopathologic features of this rare condition.
My notes (saved in your browser only)
Condition tags
MeSH descriptors
Citation neighborhood (2-hop)
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]
Cited by (50)
- Cytomorphological Diagnosis of Primary Umbilical Endometriosis (Villar’s Nodule) 2026
- Idiopathic Abdominal Wall Endometrioma: Case Report with Investigation of the Pathological, Molecular Cytogenetic and Cell Growth Features In Vitro 2025
- Characterising umbilical abdominal wall endometriosis as a distinct subgroup of abdominal wall endometriosis - retrospective cohort study 2024
- Endometriosis beyond the Pelvis: A Case Series of Cutaneous Endometriosis and Literature Review 2024
- Successful adnexectomy and umbilicoplasty for concomitant umbilical and ovarian endometriosis via a modified abdominal insufflation method 2023
- Primary Umbilical Endometriosis Coexisting with Multiple Uterine Myomas : A Rare Case Report 2023
- A case report on Spontaneous Abdominal Wall Endometriosis 2023
- Menstruating umbilicus: secondary subcutaneous umbilical endometriosis: a rare case report 2022
- Management options for primary umbilical endometriosis: a case report 2022
- Umbilical Endometriosis: A Systematic Literature Review and Pathogenic Theory Proposal 2022
- Primary Umbilical endometriosis - case series and review of clinical presentation, diagnosis and management 2022
- Coexistence of cutaneous endometriosis and ovarian endometrioma: a case report 2022
- [Umbilical endometriosis] 2022
- A Case of Primary Endometriosis Associated With an Umbilical Hernia 2022
- Endométriose cutanée ombilicale primitive 2022
- “Umbilical mass”: a case of primary umbilical endometriosis and literature review 2021
- Menstruating primary umbilicus cutaneous endometriosis: A case report and review of literature 2021
- Clinical features, diagnosis, and management of abdominal wall endometriosis: a review 2020
- Cutaneous endometriosis of the umbilicus (Villar's nodule) 2020
- Postmenopausal Spontaneous Umbilical Endometriosis: A Case Report 2020
- Cutaneous Endometriosis: A Differential Diagnosis of Umbilical Nodule 2020
- An unusual case of primary umbilical endometriosis 2020
- Clinical practice guidelines for the treatment of extragenital endometriosis in Japan, 2018 2020
- Primary Umbilical Endometriosis in an Adolescent Girl: Unsuspected Pathology 2020
- Primary Subcutaneous Umbilical Endometriosis: Case Report and Review of the Literature 2020
- Epidemiology of Bowel Endometriosis 2020
- Total Surgical Excision by Ultrasound–Guided Wire Localization for Spontaneous Abdominal-Wall Endometriosis 2019
- A Curious Case of Recurrent Umbilical Swelling: Case Report and Literature Review 2018
- Spontaneous cutaneous endometriosis of the mons pubis: Diagnosis, treatment, and review of the literature 2018
- Unus pro omnibus, omnes pro uno: A novel, evidence-based, unifying theory for the pathogenesis of endometriosis 2017
- Endometriosis cutánea espontánea 2017
- Cutaneous endometriosis: Presentation of 33 cases and literature review 2017
- Primary Cutaneous Endometriosis of Umbilicus 2017
- [Cutaneous endometriosis] 2017
- Primary umbilical endometriosis: Menstruating from the umbilicus 2017
- Spontaneous Abdominal Wall Endometriosis Diagnosed by Fine Needle Cytology: A Case Report 2017
- Primary umbilical endometriosis: a case report 2017
- Spontaneous Cutaneous Endometriosis of the Umbilicus: A Case Report 2017
- Spontaneous endometriosis associated with an umbilical hernia: A case report and review of the literature 2016
- Primary umbilical endometriosis (PUE) 2016
- A rare case of primary umbilical endometriosis in a nulliparous female confirmed on imaging and histopathology: Case report 2016
- Umbilical Nodule with Cyclical Bleeding: A Case Report and Literature Review of Atypical Endometriosis 2016
- PRIMARY UMBILICAL ENDOMETROSIS 2015
- Primary umbilical endometrioma: Analyzing the pathogenesis of endometriosis from an unusual localization 2015
- Endometriosis primaria: un diagnóstico diferencial dentro de las lesiones nodulares umbilicales 2014
- Primary umbilical endometriosis: a case report and review of literature 2014
- Primary Endometriosis of Umbilical Scar: Case Report and Review of Literature 2014
- Umbilical endometriosis with giant degenerated uterine leiomyomas: A case report 2014
- Umbilical Endometriosis without Pelvic Surgery 2014
- Lumbar Ureteral Stenosis due to Endometriosis: Our Experience and Review of the Literature 2013
Source provenance
- europepmc
- last seen: 2026-10-12T06:17:10.165071+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:09:19.025198+00:00
License: CC0
· commercial use OK