Primary Vaginal Adenosarcoma With Sarcomatous Overgrowth Arising in Recurrent Endometriosis: Feasibility of Laparoscopic Treatment and Review of the Literature
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This paper reports on a rare case of primary vaginal adenosarcoma with sarcomatous overgrowth originating in recurrent endometriosis, assessing the feasibility of laparoscopic treatment.
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Abstract
We report a case of a primary vaginal adenosarcoma with sarcomatous overgrowth in a postmenopausal 58-year-old woman with recurrent endometriosis. In the past 5 years she underwent several biopsies of a polypoid lesion on the vaginal cuff, and the last histologic examination of the biopsy showed an adenosarcoma with "sarcomatous overgrowth" in a background of endometriosis. There was no evidence of distant metastatic disease on the diagnostic workup, and we performed a laparoscopy to remove the pelvic mass. We reviewed the literature on the electronic databases Medline, Embase, and Science Direct on articles published in English from 1990 to 2015. We identified 5 articles in which the surgical treatment was performed via a laparotomic approach. The present case is the first in the literature to report feasibility of laparoscopic treatment for this kind of pathology with a detailed description of the surgical technique.
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Cited by (12)
- Active surveillance of an endometriosis-related, hormone-responsive pelvic adenosarcoma during pregnancy: A case report 2026
- Case Report: Malignant transformation of deep infiltrating endometriosis: a report of two cases and literature review 2026
- Ovarian adenosarcoma in a postmenopausal woman: Case report and review of literature 2023
- Malignant Transformation of Postmenopausal Endometriosis: A Systematic Review of the Literature 2021
- Endometriosis: A Malignant Fingerprint 2020
- Two Cases of Extrauterine Müllerian Adenosarcoma Arising from Pelvic Endometriosis 2019
- Diagnostic challenges: low-grade adenosarcoma on deep endometriosis 2019
- Primary extra-uterine and extra-ovarian mullerian adenosarcoma: case report and literature review 2018
- Inhibitory effect of curcumin in human endometriosis endometrial cells via downregulation of vascular endothelial growth factor 2017
- Endometrial Stromal Sarcoma Arising from Endometriosis 2017
- Reply to "Primary Vaginal Adenosarcoma With Sarcomatous Overgrowth Arising in Recurrent Endometriosis: Feasibility of Laparoscopic Treatment and Review of the Literature" 2016
- Malignant Transformation of Vaginal Endometriosis - A Review of Literature 2016
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- europepmc
- last seen: 2026-10-25T09:32:14.900964+00:00
- openalex
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- pubmed
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