Sleep disturbances, fatigue and psychological health in women with endometriosis: a matched pair case-control study

Facchin F, Federica Facchin, Buggio L, Laura Buggio, Roncella E, Elena Roncella, Edgardo Somigliana, Somigliana E, Federica Ottolini, Ottolini F, Dhouha Dridi, Roberto A, Roberto Ratiglia, Anna Roberto, Paolo Vercellini
Reproductive BioMedicine Online · 2021 · vol. 43(6) , pp. 1027–1034 · doi:10.1016/j.rbmo.2021.08.011 · PMID:34756643 · W3194209472
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This study investigated sleep disturbances, fatigue, and psychological health in women with endometriosis compared to matched controls without the condition.

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Abstract

RESEARCH QUESTION: What are the associations between endometriosis, pelvic pain symptoms, fatigue and sleep? Psychological health and quality of life in endometriosis patients with good versus bad quality of sleep were also examined. DESIGN: This matched pair case-control study included 123 consecutive endometriosis patients and 123 women without a history of endometriosis (matched to patients for age and body mass index). Endometriosis-related pelvic pain severity was rated on a 0-10 numerical rating scale. Fatigue was measured on a 1-5 Likert scale. Women also completed a set of self-report questionnaires for assessing sleep disturbances (Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, Insomnia Severity Index), psychological health (Hospital Anxiety and Depression Scale) and quality of life (Short Form-12). RESULTS: Painful endometriosis had an impact on fatigue (P = 0.006; η2p = 0.041) and sleep (P < 0.001; η2p = 0.051). Women with painful endometriosis reported significantly greater fatigue, poorer quality of sleep, higher daytime sleepiness and more severe insomnia than women without significant pain symptoms and controls. Poorer quality of sleep among endometriosis patients was associated with greater fatigue (P < 0.001; η2p = 0.130), poorer psychological health (P < 0.001; η2p = 0.135), and lower quality of life (P < 0.001; η2p = 0.240). CONCLUSIONS: Pelvic pain (rather than endometriosis in itself) is associated with fatigue and sleep disturbances, with poor sleep having a detrimental impact on women's psychological health and quality of life.

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Endometriosis Fatigue Mental Health Mental Health Pelvic Pain Quality of Life Quality of Life Sleep Wake Disorders Adult Adult Age Factors Age Factors Body Mass Index Body Mass Index Case-Control Studies Case-Control Studies Endometriosis Endometriosis Endometriosis Fatigue

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (39)

Cited by (24)

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