Current understanding of endometrial stem cells

Irene Cervelló Alcaraz, Claudia Gil-Sanchís, Aymara Mas Perucho, Carlos Simón
In: Expert Review of Obstetrics & Gynecology · 2009 · vol. 4(3) , pp. 273–282 · doi:10.1586/eog.09.12 · W2164692268
Review OA: closed CC0 ⤵ 1 in-corpus citation
View on OpenAlex View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-09 ⓘ

Endometrial stem cells, defined by functional properties due to lacking specific markers, are present in human and murine endometria and are presumed to have a mesenchymal origin, though further research is needed to understand their role in gynecological disorders.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Somatic stem cells (SSCs) are defined as a rare population of undifferentiated cells residing in differentiated tissues and organs. Different studies and diverse approaches suggest the presence of SSCs in human and murine endometria. Owing to the lack of specific phenotypic markers to identify endometrial SSCs, they are defined by their functional properties. The embryological origin of the uterus and the putative implication of bone marrow in endometrial regeneration suggest their presumed mesenchymal origin. Nevertheless, more information is needed regarding the physiology of endometrial stem cells to understand the gynecological disorders associated with abnormal endometrial proliferation, such as endometriosis and endometrial cancer.

My notes (saved in your browser only)

Condition tags

endometriosis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (93)

Cited by (1)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
unpaywall
last seen: 2026-10-24T06:30:43.844863+00:00
License: CC0 · commercial use OK