CA 125 in Benign Gynecological Conditions
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CA 125 levels can be elevated in various benign gynecological conditions, indicating it is a non-specific marker for peritoneal issues rather than solely ovarian malignancies.
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Abstract
The tumor marker CA 125 was initially thought to be specific for ovarian malignancies. Subsequently it was found to be raised in a variety of benign conditions, including pregnancy, pelvic inflammatory disease, tuberculosis and cirrhosis of the liver. With respect to gynecological tumors, CA 125 may be elevated in benign ovarian cysts, tubo-ovarian abscess, endometriosis, hyperstimulation syndrome, ectopic pregnancy and fibroids. These results demonstrate that CA 125 is a marker of non-specific peritoneal conditions.
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Cited by (18)
- Validation of an In Vitro Diagnostic Test for Endometriosis: Impact of Confounding Medical Conditions and Lesion Location 2024
- Current evidence on CA-125 levels in differentiation between endometriomas and endometriosis-associated ovarian cancer – A systematic review and meta-analysis 2024
- Validation of an in vitro diagnostic test for endometriosis: impact of confounding medical conditions and lesion location 2024
- The Level of Ca125 in Preand Postoperative of Endometriosis 2017
- Severe adenomyosis and CA125 2013
- Serum HE4 concentration is not dependent on menstrual cycle or hormonal treatment among endometriosis patients and healthy premenopausal women 2012
- Useful Biomarkers for the Diagnosis of Endometriosis 2010
- ORIGINAL ARTICLE: Endometrial Osteopontin mRNA Expression and Plasma Osteopontin Levels are Increased in Patients with Endometriosis 2009
- Adenomyosis With Extremely Elevated CA 125 Levels 2009
- Genetic alterations of HOXA10 and their effect on the severity of endometriosis in a Taiwanese population 2008
- Genetic alterations of HOXA10 and their effect on the severity of endometriosis in a Taiwanese 2008
- Elevation of serum CA 125 and D-dimer levels associated with rupture of ovarian endometrioma 2007
- Elevation of Serum CA 125 and D-Dimer Levels associated with Rupture of Ovarian Endometrioma 2007
- Elevation of CA 19‐9 and chromogranin A, in addition to CA 125, are detectable in benign tumors in leiomyomas and endometriosis 2007
- Serum and peritoneal abnormalities in endometriosis: potential use as diagnostic markers. 2006
- Catamenial pneumothorax and other thoracic manifestations of endometriosis 2004
- Serum and Peritoneal Markers for Endometriosis 2003
- Adenomyosis: an aid to diagnosis? 2003
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