Low LH (Hcg) Receptor Concentration in Ovarian Follicles in Endometriosis

A Kauppila, Antti Kauppila, Kauppila A, H Rajaniemi, Rajaniemi H, Hannu Rajaniemi, Rönnberg L, Lars Rönnberg, L Rönnberg
Acta obstetricia et gynecologica Scandinavica · 1982 · vol. 61(1) , pp. 81–83 · doi:10.3109/00016348209156957 · PMID:6283782 · W1984668030
article OA: closed CC0 ⤵ 10 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-13 ⓘ

Granulosa cells of ovarian follicles in women with endometriosis showed lower LH (hCG) receptor concentrations compared to controls, indicating a potential failure in LH action mediation.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

The concentration of LH (hCG) receptors in the granulosa cells of ovarian follicles was assayed in 20 patients with histologically proven endometriosis and in 6 control patients. The levels of receptors in 15 patients with ovarian endometriosis (0.48 +/- 0.46 fmol/mg protein) and in 5 patients with endometriosis without ovarian involvement (0.51 +/- 0.52 fmol/mg protein) were lower (p less than 0.01 and p less than 0.05, respectively) than in control patients (1.32 less than 0.61 fmol/mg protein). The severity of the disease was not reflected in the results. The low receptor concentration in endometriosis suggests a failure in the mechanism mediating LH action in the follicle.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Endometriosis Ovarian Follicle Receptors, Cell Surface Adult Chorionic Gonadotropin Chorionic Gonadotropin Endometriosis Female Humans Luteinizing Hormone Luteinizing Hormone Middle Aged Ovarian Follicle Receptors, Cell Surface Receptors, LH

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (13)

Cited by (10)

Source provenance

europepmc
last seen: 2026-07-26T06:08:39.051465+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:10:06.101301+00:00
unpaywall
last seen: 2026-07-26T06:48:27.953686+00:00
License: CC0 · commercial use OK