Low LH (Hcg) Receptor Concentration in Ovarian Follicles in Endometriosis
article
OA: closed
CC0
⤵ 10 in-corpus citations
Abstract
The concentration of LH (hCG) receptors in the granulosa cells of ovarian follicles was assayed in 20 patients with histologically proven endometriosis and in 6 control patients. The levels of receptors in 15 patients with ovarian endometriosis (0.48 +/- 0.46 fmol/mg protein) and in 5 patients with endometriosis without ovarian involvement (0.51 +/- 0.52 fmol/mg protein) were lower (p less than 0.01 and p less than 0.05, respectively) than in control patients (1.32 less than 0.61 fmol/mg protein). The severity of the disease was not reflected in the results. The low receptor concentration in endometriosis suggests a failure in the mechanism mediating LH action in the follicle.
My notes (saved in your browser only)
Condition tags
MeSH descriptors
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
References (13)
- A STUDY OF PLASMA PROGESTERONE, OESTRADIOL‐l7β, PROLACTIN AND LH LEVELS, AND OF THE LUTEAL PHASE APPEARANCE OF THE OVARIES IN PATIENTS WITH ENDOMETRIOSIS AND INFERTILITY via openalex
- Endometriosis and anovulation: A coexisting problem in the infertile female via openalex
- Endometriosis: Associations with Menorrhagia, Infertility and Oral Contraceptives via openalex
- New aspects of the pathophysiology of endometriosis and associated infertility. via openalex
- The Luteinized Unruptured Follicle Syndrome and Endometriosis via openalex
- W2068655375 via openalex
- W2084004667 via openalex
- W74305887 via openalex
- W2410955081 via openalex
- W1775749144 via openalex
- W1983649348 via openalex
- W2039353201 via openalex
- W2043940551 via openalex
Cited by (10)
- Downregulation of LHCGR Attenuates COX-2 Expression and Induces Luteinized Unruptured Follicle Syndrome in Endometriosis 2022
- A case of spontaneous abortion related to ovarian endometriosis in a Golden Retriever dog. 2017
- Medikamentöse und konservative Therapie 2004
- Rezidivierende Endometriose?ein Kofaktor der vorzeitigen Menopause? 2003
- Elevated expression of tumour necrosis factor α in cultured granulosa cells from women with endometriosis 2000
- Pathophysiology of Endometriosis-Associated Infertility 1999
- Immunoreactive endothelin-1 concentrations in follicular fluid of women with and without endometriosis undergoing in vitro fertilization-embryo transfer 1994
- Endometriosis as a Cause of Infertility 1989
- Decreased concentration of ovarian LH(hCG) receptor in polycystic ovarian disease and endometriosis 1984
- Luteinizing hormone receptor disorder in endometriosis 1984
Source provenance
- europepmc
- last seen: 2026-06-11T06:19:48.454388+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:10:06.101301+00:00
- unpaywall
- last seen: 2026-06-02T02:00:03.124865+00:00
License: CC0
· commercial use OK