Endometriosis: symptoms, diagnosis, and treatment

In: International journal of health sciences · 2017 · vol. 1(S1) , pp. 228–238 · doi:10.53730/ijhs.v1ns1.15299 · W4404014365
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This review examines surgical and hormonal treatments for endometriosis-related pain and infertility, noting high surgical success rates but also significant recurrence risk.

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This paper reviews existing literature on current clinical management of endometriosis, focusing on treatment of pain and infertility using surgical and medical approaches, and synthesizing reported efficacy and considerations for surgical intervention. It reports that surgical techniques such as excision of endometrial implants and nerve ablation have success rates of 50% to 80% for alleviating symptoms, while first-line pain therapies include NSAIDs, combined oral contraceptive pills, progestins, and GnRH agonists. For infertility, it notes that surgical interventions can improve the likelihood of natural conception, but it also highlights recurrence of endometriosis as a significant concern, with rates of 5% to 15% even after comprehensive surgeries. This paper is centrally about endometriosis — it reviews symptoms, diagnosis, and multidisciplinary pain and infertility management strategies, including surgical and hormonal treatments.

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Abstract

Background: Endometriosis is a complex gynecological condition characterized by the presence of endometrial-like tissue outside the uterus, often leading to chronic pain and infertility. Its management requires a multidisciplinary approach that includes surgical and medical interventions. Aim: This article aims to review current clinical management practices for pain and infertility associated with endometriosis, focusing on surgical and hormonal treatments as well as pain management strategies. Methods: A comprehensive analysis of existing literature on endometriosis management was conducted, highlighting various therapeutic options, their efficacy, and considerations regarding surgical interventions. Results: Surgical techniques, such as excision of endometrial implants and nerve ablation, demonstrate success rates of 50% to 80% in alleviating symptoms. Hormonal treatments, including non-steroidal anti-inflammatory drugs (NSAIDs), combined oral contraceptive pills (COCPs), progestins, and gonadotropin-releasing hormone agonists (GnRH), are first-line therapies for managing pain. In cases of infertility, surgical interventions can enhance the likelihood of natural conception. However, the recurrence of endometriosis remains a significant concern, occurring in 5% to 15% of patients even after comprehensive surgeries. Conclusion: Effective management of endometriosis-related pain and infertility necessitates a tailored approach, considering patient preferences, side effects, and the specific clinical scenario.
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Keywords

Endometriosis, pain management, infertility, surgical treatment, hormonal therapy, multidisciplinary approachAbstract

Background

Endometriosis is a complex gynecological condition characterized by the presence of endometrial-like tissue outside the uterus, often leading to chronic pain and infertility. Its management requires a multidisciplinary approach that includes surgical and medical interventions. Aim: This article aims to review current clinical management practices for pain and infertility associated with endometriosis, focusing on surgical and hormonal treatments as well as pain management strategies. Methods: A comprehensive analysis of existing literature on endometriosis management was conducted, highlighting various therapeutic options, their efficacy, and considerations regarding surgical interventions. Results: Surgical techniques, such as excision of endometrial implants and nerve ablation, demonstrate success rates of 50% to 80% in alleviating symptoms. Hormonal treatments, including non-steroidal anti-inflammatory drugs (NSAIDs), combined oral contraceptive pills (COCPs), progestins, and gonadotropin-releasing hormone agonists (GnRH), are first-line therapies for managing pain. In cases of infertility, surgical interventions can enhance the likelihood of natural conception. However, the recurrence of endometriosis remains a significant concern, occurring in 5% to 15% of patients even after comprehensive surgeries. Conclusion: Effective management of endometriosis-related pain and infertility necessitates a tailored approach, considering patient preferences, side effects, and the specific clinical scenario. Downloads

References

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