The expression of microRNA-451 in human endometriotic lesions is inversely related to that of macrophage migration inhibitory factor (MIF) and regulates MIF expression and modulation of epithelial cell survival
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MicroRNA-451 expression is elevated in endometriotic lesions, where it inversely regulates macrophage migration inhibitory factor and modulates epithelial cell survival.
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Abstract
study question: What is the role of microRNA-451 (miR-451) in human endometriotic tissue? summary answer: miR451 expression was elevated in endometriotic lesion tissue. MiR451 modulated the expression of macrophage migration inhibitory factor and limited cell survival.
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Cited by (33)
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- DECREASED EXPRESSION OF MIRNA451 IN THE ENDOMETRIUM OF WOMEN WITH ENDOMETRIOSIS IN THE SECRETORY PHASE OF THE UTERUS 2023
- Dissecting the miR-451a-Mif Pathway in Endometriosis Pathophysiology Using a Syngeneic Mouse Model: Temporal Expression of Lesion Mif Receptors, Cd74 and Cxcr4 2022
- The Relationship and Expression of miR-451a, miR-25-3p and PTEN in Early Peritoneal Endometriotic Lesions and Their Modulation In Vitro 2022
- Inflammatory MicroRNAs and the Pathophysiology of Endometriosis and Atherosclerosis: Common Pathways and Future Directions Towards Elucidating the Relationship 2022
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- Circulating miRNAs Related to Epithelial–Mesenchymal Transitions (EMT) as the New Molecular Markers in Endometriosis 2021
- microRNA and Overcoming the Challenges of Their Use in the Diagnosis of Endometriosis 2020
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- How Benign is Endometriosis: Multi-Scale Interrogation of Documented Evidence 2019
- Plasma miRNAs Display Limited Potential as Diagnostic Tools for Endometriosis 2019
- miR-45la Inhibition Reduces Established Endometriosis Lesions in Mice 2019
- Reduced microRNA-451 expression in eutopic endometrium contributes to the pathogenesis of endometriosis 2019
- 60S acidic ribosomal protein P1 (RPLP1) is elevated in human endometriotic tissue and in a murine model of endometriosis and is essential for endometriotic epithelial cell survival <i>in vitro</i> 2019
- Human endometriotic lesion expression of the miR-144-3p/miR-451a cluster, its correlation with markers of cell survival and origin of lesion content 2019
- MicroRNAs in endometriosis: biological function and emerging biomarker candidates† 2019
- Macrophage Migration Inhibitory Factor Receptor, CD74, is Overexpressed in Human and Baboon (Papio Anubis) Endometriotic Lesions and Modulates Endometriotic Epithelial Cell Survival and Interleukin 8 Expression 2018
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- last seen: 2026-06-04T00:00:01.174412+00:00
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