Leuprolide acetate in the management of cesarean scar endometriosis

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Leuprolide acetate treatment for cesarean scar endometriosis improved patient symptoms but did not alter lesion size based on physical examination and CT scans.

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Abstract

BACKGROUND: Progestin or estrogen-progestin combination therapy has not proven useful in the treatment of endometriosis of the abdominal scar after cesarean delivery. We report our experience in managing this condition with a gonadotropin agonist. CASE: A 22-year-old black woman with a history of two previous cesareans developed endometriosis of the abdominal scar. The extent of the lesion was estimated by computed tomographic (CT) scan, and a 6-month preoperative course of leuprolide acetate was administered. The patient exhibited prompt symptomatic response to the gonadotropin agonist, but the physical examination and CT scan findings were unchanged. Pathologic examination after surgical removal of the lesion confirmed the clinical diagnosis. CONCLUSION: Leuprolide acetate administered to a patient with cesarean scar endometriosis was associated with an improvement in symptoms, but there was no change in lesion size.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Postoperative Complications Adult Adult Cesarean Section Cesarean Section Cesarean Section Cicatrix Cicatrix Cicatrix Endometriosis Endometriosis Endometriosis Endometriosis Female Female Humans Humans Leuprolide Leuprolide

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (3)

Cited by (50)

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License: CC0 · commercial use OK