Study of preoperative GnRh agonist in cutaneous scar endometriosis

Nitin Kulkarni, Ashwini Patil, Richa Patel
In: International Journal of Reproduction, Contraception, Obstetrics and Gynecology · 2016 · pp. 3191–3194 · doi:10.18203/2320-1770.ijrcog20163010 · W2516261057
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

Preoperative GnRH agonist therapy prior to surgical excision of cutaneous scar endometriosis aids in easier excision and reduces recurrence rates.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 · read from full text ⓘ

This prospective randomized case-control study evaluated preoperative GnRH agonist therapy in patients with cutaneous scar endometriosis undergoing surgical excision, with all cases operated and followed up by the same surgeon. The key reported finding was that combining surgical excision with preoperative GnRH agonist was helpful for easier excision and for reducing recurrence, with the paper presenting this as the study objective’s outcome. A major limitation is that the abstract does not provide diagnostic methods, sample size, randomization details, or quantitative recurrence results, which constrains interpretation of effect size. This paper is centrally about endometriosis — it specifically studies preoperative GnRH agonist use to improve outcomes in cutaneous scar endometriosis.

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Abstract

Background: Cutaneous scar endometriosis is an uncommon pathology, it is rare and difficult to diagnose, mostly follows obstetrical and gynaecological surgeries. Surgical wide excision is the mainstay of treatment. The objective of this study was to evaluate efficacy of preoperative GnRh agonist in scar endometriosis.Methods: This is prospective randomized case control study performed on all cutaneous scar endometriosis cases reporting to our institute as well as consultants from Dhule obstetrics and gynaecology society. All cases were operated and follow up in our institute by same surgeon.Results: Surgical excision accompanied by preoperative GnRh agonist therapy is helpful for easy excision and reduce recurrence of scar endometriosis.Conclusions: Abdominal scar endometriosis is rare gynecological pathology, should be suspected in any women of child bearing age group complaining of cyclical painful nodule in scar following a previous obstetric and gynaecological procedure.
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Background

Cutaneous scar endometriosis is an uncommon pathology, it is rare and difficult to diagnose, mostly follows obstetrical and gynaecological surgeries. Surgical wide excision is the mainstay of treatment. The objective of this study was to evaluate efficacy of preoperative GnRh agonist in scar endometriosis.

Methods

This is prospective randomized case control study performed on all cutaneous scar endometriosis cases reporting to our institute as well as consultants from Dhule obstetrics and gynaecology society. All cases were operated and follow up in our institute by same surgeon.

Results

Surgical excision accompanied by preoperative GnRh agonist therapy is helpful for easy excision and reduce recurrence of scar endometriosis.

Conclusions

Abdominal scar endometriosis is rare gynecological pathology, should be suspected in any women of child bearing age group complaining of cyclical painful nodule in scar following a previous obstetric and gynaecological procedure.Metrics

References

Nahir B, Eldar-Geva T, Alberton J, Beller U. Symptomatic diaphragmatic endometriosis ten years after total abdominal hysterectomy. Obstetrics and gynecology. 2004;104(5):1149-51. Drukala Z, Ciborowska-Zielińska B, Kubrak J, Rodgowska D. Outcome of a multimodal therapy of a recurrent adenocarcinoma arising from Caesarean section scar endometriosis- a case report. Reports of Practical Oncology and Radiotherapy. 2010;15(3). Jubanyik KJ, Committee F. Extrapelvic endometriosis. Obstetrics and Gynecology Clinics of North America. 1997;24(2):411-40. Medeiros FD, Cavalcante DI, Medeiros MA, Eleuterio J. Fine‑Need leaspiration cytology of scar endometriosis: study of seven cases and literature review. Diagn Cytopathol. 2011;39:18‑21. Nominato SN, Prates LF, Lauar I, Morais J, Maia L, Geber S. Caesarean section greatly increases the risk of scar endometriosis. European Journal of Obstetrics and Gynecology and Reproductive Biology. 2010;152:83-5. Dwivedi AJ, Agrawal SN, Silva YJ. Abdominal wall endometrioma. Digestive Diseases and Sciences. 2002;47(2):456-61. Medeiros FD, Cavalcante DI, Medeiros MA, Eleuterio J. Fine‑needle aspiration cytology of scar endometriosis: study of seven literature review. Diagn Cytopathol. 2011;39:18‑21. Pathan ZA, Dinesh US, Rao R. Scar endometriosis. J Cytology. 2010;27:106‑8. Koger KE, Shatney CH, Hodge K, McClenathan JH. Surgical scar endometrioma. Surgery Gynecology and Obstetrics. 1993;177(3):243-6. Wolf Y, Haddad R, Werbin N, Skornick Y, Kaplan O. Endometriosis in abdominal scars: a diagnostic pitfall. American Surgeon. 1996;62(12):1042-4. Aydin O. Scar endometriosis a gynaecologic pathology often presented to the general surgeon rather than the gynaecologist: report of two cases. Langenbeck’s Archives of Surgery. 2007;392(1):105-9. Picod G, Boulanger L, Bounoua F, Leduc F, Duval G. Abdominal wall endo-metriosis after cesarean section: report of fifteen cases. Gynecol Obstet Fertil. 2006;34:8-13. Pathan SK, Kapila K, Haji BE, Mallik MK, Al-Ansary TA, George SS, et al. Cytomorphological spectrum in scar endometriosis: a study of eight cases. Cytopathology. 2005;16(2):94-9. Rani PR, Soundararaghavan S, Rajaram P. Endometriosis in abdominal scars review of 27 cases. International Journal of Gynecology and Obstetrics. 1991;36(3):215-8. Rivlin ME, Das SK, Patel RB, Meeks GR. Leuprolide acetate in the management of cesarean scar endometriosis. Obstet Gynecol. 1995;85:838-9.

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endometriosis

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