A case series of scar endometriosis: a mysterious painful scar

In: International Journal of Reproduction, Contraception, Obstetrics and Gynecology · 2025 · vol. 14(10) , pp. 3511–3515 · doi:10.18203/2320-1770.ijrcog20253100 · W4414556408
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This case series describes five patients with scar endometriosis, highlighting variable presentations, the importance of surgical history, and the diagnostic utility of post-operative histopathology following wide local excision.

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This case series studied scar endometriosis in five patients, describing variable presentations in a context where patients often first present to general surgery rather than gynecology, with prior obstetric history (especially cesarean section) emphasized as important for diagnosis. The key finding was that all diagnoses were confirmed with post-operative histopathology, and patients were offered wide local excision as treatment, while the paper also discusses proposed pathogenesis, treatment, and prevention. A major limitation is the small, case-series design without comparative outcomes or explicit quantification of recurrence. This paper is centrally about endometriosis — specifically scar endometriosis presenting as a painful scar after surgical procedures such as cesarean section.

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Abstract

Endometriosis is the presence of endometrial tissue outside the uterine cavity. Scar endometriosis, one of its rare variants, is the study of interest since most of the patients present to the general surgeon rather than to a gynaecologist due to its quite often non-specific symptoms. In this case series of 5 patients, 2 of the patients had presented to the general surgery department, one presented with non-specific symptom. Prior history of any obstetric (caesarean section in particular) and gynaecological surgeries must be elicited which may help in clinching towards the diagnosis. This report is about a case series of 5 patients who had variable presentations and were offered wide local excision. Diagnosis was confirmed with post-operative histopathology. The pathogenesis, treatment and prevention have been discussed.
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A case series of scar endometriosis: a mysterious painful scar DOI: https://doi.org/10.18203/2320-1770.ijrcog20253100Keywords: Caesarean section, Endometriosis, Wide local excisionAbstract Endometriosis is the presence of endometrial tissue outside the uterine cavity. Scar endometriosis, one of its rare variants, is the study of interest since most of the patients present to the general surgeon rather than to a gynaecologist due to its quite often non-specific symptoms. In this case series of 5 patients, 2 of the patients had presented to the general surgery department, one presented with non-specific symptom. Prior history of any obstetric (caesarean section in particular) and gynaecological surgeries must be elicited which may help in clinching towards the diagnosis. This report is about a case series of 5 patients who had variable presentations and were offered wide local excision. Diagnosis was confirmed with post-operative histopathology. The pathogenesis, treatment and prevention have been discussed. Metrics References Singh S, Dharwadkar M. Case series of scar endometriosis- post caeserean section: A diagnostic pitfall. Indian J Obstet Gynecol Res. 2021;8(4):454-6 DOI: https://doi.org/10.18231/j.ijogr.2021.095 Bansal K. Manual of endometriosis. JP Medical Ltd. 2013. Francica G, Giardiello C, Angelone G, Cristiano S, Finelli R, Tramontano G. Abdominal wall endometriosis near cesarean delivery scars. J Ultrasound Med. 2003;22:1041–7. Kaloo P, Reid G, Wong F. Caesarean section scar endometriosis: Two cases of recurrent disease and a literature review. Aust NZ J Obstet Gynaecol. 2002;42:218–20. DOI: https://doi.org/10.1111/j.0004-8666.2002.210_5.x J Danielpour P, C Layke Do J, Durie N, T Glickman L. Scar endometriosis–a rare cause for a painful scar: A case report and review of the literature. Canadian J Plast Surg. 2010;18(1):19-20. DOI: https://doi.org/10.1177/229255031001800110 Sasson IE, Taylor HS. Stem cells and the pathogenesis of endometriosis. Ann New York Acad Sci. 2008;1127(1):106-15. DOI: https://doi.org/10.1196/annals.1434.014 Nondecidualized and decidualized endometriosis of the abdominal wall (A report of two cases secondary to cesarean section) Turk J Med Sci. 2002;32:505-8. Mathur S, Peress HO, Williamson CD, Youmans SA, Maney AJ. Autoimmunity to endometrium and ovary in endometriosis. Clin Exp Immunol. 1982;50(2):259. Wang PH, Juang CM, Chao HT, Yu KJ, Yuan CC, Ng HT. Wound endometriosis: risk factor evaluation and treatment. J Chinese Med Assoc. 2003;66(2):113-9. Wicherek L, Klimek M, Skret-Magierlo J, Czekierdowski A, Banas T, Popiela TJ, et al. The obstetrical history in patients with Pfannenstiel scar endometriomas–an analysis of 81 patients. Gynecol Obstet Invest. 2007;63(2):107-13. DOI: https://doi.org/10.1159/000096083 Paşalega M, Mirea C, Vîlcea ID, Vasile I, Pleşea IE, Calotă F, et al. Parietal abdominal endometriosis following Cesarean section. Rom J Morphol Embryol. 2011;52(1):503-8. Goel P, Devi L, Tandon R, Saha PK, Dalal A. Scar endometriosis–a series of six patients. International J Surg. 2011;9(1):39-40. DOI: https://doi.org/10.1016/j.ijsu.2010.08.003 Gupta RK. Fine‐needle aspiration cytodiagnosis of endometriosis in cesarean section scar and rectus sheath mass lesions—A study of seven cases. Diagnostic Cytopathol. 2008;36(4):224-6. DOI: https://doi.org/10.1002/dc.20797 Francica G, Giardiello C, Angelone G, Cristiano S, Finelli R, Tramontano G. Abdominal wall endometriomas near cesarean delivery scars: sonographic and color doppler findings in a series of 12 patients. J Ultras Med. 2003;22(10):1041-7. DOI: https://doi.org/10.7863/jum.2003.22.10.1041 Savelli L, Manuzzi L, Di Donato N, Salfi N, Trivella G, Ceccaroni M. Endometriosis of the abdominal wall: ultrasonographic and Doppler characteristics. Ultras Obst Gynecol. 2012;39(3):336-40. DOI: https://doi.org/10.1002/uog.10052 Blanco RG, Parithivel VS, Shah AK, Gumbs MA, Schein M, Gerst PH. Abdominal wall endometriomas. The American J Surg. 2003;185(6):596-8. DOI: https://doi.org/10.1016/S0002-9610(03)00072-2 Marras S, Pluchino N, Petignat P, Wenger JM, Ris F, Buchs NC, Dubuisson J. Abdominal wall endometriosis: An 11-year retrospective observational cohort study. European J Obst Gynecol Reprod Bio. 2019;4:100096. DOI: https://doi.org/10.1016/j.eurox.2019.100096 Rivlin ME, Das SK, Patel RB, Meeks GR. Leuprolide acetate in the management of cesarean scar endometriosis. Obstet Gynecol. 1995;85(5):838-9. DOI: https://doi.org/10.1016/0029-7844(94)00270-N Wang SK, Lee MW, Choi JH, Sung KJ, Moon KC, Koh JK. Cutaneous endometriosis: a combination of medical and surgical treatment. J Dermatol Treat. 2002;13(4):189-92. DOI: https://doi.org/10.1080/09546630212345677 Wasfie T, Gomez E, Seon S, Zado B. Abdominal wall endometrioma after cesarean section: a preventable complication. Int Surg. 2002;87(3):175-7. Nigam A, Saxena P, Barla J, Pathak P. Scar endometriosis: the menace of surgery. BMJ Case Rep. 2014;15;2014. DOI: https://doi.org/10.1136/bcr-2014-206693 Picod G, Boulanger L, Bounoua F, Leduc F, Duval G. Abdominal wall endometriosis after caesarean section: report of fifteen cases. Gynecol Obstetr Fert. 2006;34(1):8-13. DOI: https://doi.org/10.1016/j.gyobfe.2005.11.002 Minaglia S, Ballard A. “Incisional endometriomas after cesarean section: a case series. J Reprod Med 2007;52(7):630-4.

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