Scar Endometriosis – a Rare Cause for a Painful Scar: A Case Report and Review of the Literature

Danielpour PJ, Payman J. Danielpour, John C. Layke, Layke JC, Nicole Durie, Durie N, Glickman LT, Laurence T. Glickman
The Canadian journal of plastic surgery = Journal canadien de chirurgie plastique · 2010 · vol. 18(1) , pp. 19–20 · doi:10.1177/229255031001800110 · PMID:21358869 · PMC2851454 · W1889902754
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This case report describes scar endometriosis, a rare cause of abdominal wall pain at an incision site following cesarean section, which was diagnosed and treated by surgical excision.

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This case report and literature review examines scar endometriosis, a rare condition where ectopic endometrial tissue develops within surgical incisions, typically following obstetric or gynecological procedures. The authors present a patient with a painful abdominal wall nodule at a previous cesarean section site, which was definitively diagnosed as endometriosis only after complete surgical excision and histological analysis revealed characteristic glandular and stromal elements. While hormonal suppression is sometimes attempted, the paper notes that surgical removal remains the definitive treatment for this elusive diagnosis, which often presents with nonspecific pain rather than classic cyclical symptoms. This paper is centrally about endometriosis — specifically the rare presentation of scar endometriosis in abdominal wall incisions.

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Abstract

Endometriosis is described as the presence of functioning endometrial tissue outside the uterine cavity. Scar endometriosis is a rare disease, and is difficult to diagnose. The symptoms are nonspecific, typically involving abdominal wall pain at the incision site at the time of menstruation. It commonly follows obstetrical and gynecological surgeries. The diagnosis is frequently made only after excision of the diseased tissue. A case report of a patient with a troublesome scar after a caesarian section is presented. Surgical excision led to the diagnosis of scar endometriosis. The pathogenesis, diagnosis and treatment of this somewhat rare condition are discussed.
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Abstract

Endometriosis is described as the presence of functioning endometrial tissue outside the uterine cavity. Scar endometriosis is a rare disease, and is difficult to diagnose. The symptoms are nonspecific, typically involving abdominal wall pain at the incision site at the time of menstruation. It commonly follows obstetrical and gynecological surgeries. The diagnosis is frequently made only after excision of the diseased tissue. A case report of a patient with a troublesome scar after a caesarian section is presented. Surgical excision led to the diagnosis of scar endometriosis. The pathogenesis, diagnosis and treatment of this somewhat rare condition are discussed.

Keywords

Cutaneous endometriosis, Endometriosis, Incisional endometriosis, Painful scar, Scar endometriosis

Abstract

L’endométriose se décrit par la présence de tissu endométrial fonctionnel à l’extérieur de la cavité utérine. L’endométriose cicatricielle est un problème rare difficile à diagnostiquer. Les symptômes ne sont pas spécifiques et s’associent souvent à des douleurs de la paroi abdominale au foyer de l’incision lors des menstruations. Les manifestations suivent fréquemment une opération obstétricale et gynécologique. Le diagnostic est souvent posé après l’excision du tissu atteint. Le rapport de cas d’une patiente étant incommodée par une cicatrice après une césarienne est présenté. L’excision chirurgicale a permis de diagnostiquer une endométriose cicatricielle. La pathogenèse, le diagnostic et le traitement de ce problème plutôt rare sont exposés. Endometriosis is defined as the presence or growth of ectopic endometrial tissue (1). Affecting an estimated 89 million women of reproductive age worldwide, endometriosis occurs in 5% to 10% of all women, often resulting in debilitating pain and infertility. Although most frequently found in the pelvis, reports citing extrapelvic endometrial locations range from the lungs to the extremities (2). Incisional or scar endometriosis has also been described, however, with a much rarer incidence (fewer than 1% of affected patients) (1,3). This entity can result in unnecessary procedures, delayed or misdiagnosis, and can cause emotional and physical distress to the patient. The present study describes a case of scar endometriosis, and reviews the literature to elucidate physical signs and symptoms that may lead to earlier diagnosis and prompt treatment. CASE PRESENTATION A 26-year-old African-American woman was seen in consultation for a painful abdominal scar. She was an otherwise healthy woman with no significant medical history. Her surgical history included an uncomplicated caesarian section three years previously. She complained of increasing pain and tenderness at the Pfannenstiel incisional site, but did not report any cyclical pattern associated with these symptoms. Physical examination revealed a well-healed caesarian scar, with a nonmobile, nodular, moderately pigmented area at its lateral border (Figure 1). Exquisite point tenderness to palpation over the nodular area was noted. A preliminary diagnosis of neuroma was entertained, and the patient was taken to the operating room for exploration of the abdominal wound and possible neuroma excision. Intraoperatively, extensive fibrosis of the scar to the fascia was noted. The scar was completely excised with the nodular portion, and the specimen was sent to the pathology department. The final report revealed “dermal fibrosis with endometriosis”. The patient’s postoperative course was uneventful, and her pain subsided. PATHOLOGY Endometriosis is defined by occurrence of endometrial-like epithelium and stroma outside the uterine cavity. This condition is commonly seen in females of reproductive age. Grossly, endometriosis may present as small, dark red, black or bluish cysts or nodules on the surface of peritoneal and pelvic organs. Histologically, endometriosis is characterized by the ectopic presence of endometrial-like glands, spindled endometrial stroma and hemosiderin deposition either within the macrophages or in the stroma (Figures 2 and 3). In many cases, this diagnostic triad is not present, or the glands and stroma may be obscured by hemorrhage, foamy cells and hemosiderin-laden macrophages. When this occurs, the diagnosis may be suggested but histological confirmation may not be possible.

Discussion

Scar endometriosis is a rare entity reported in the gynecological literature, and presents in women who have undergone a previous abdominal or pelvic operation (4). The incidence has been estimated to be only 0.03% to 0.15% of all cases of endometriosis (1,3). Many theories as to the cause of scar endometriosis have been postulated; however, the most generally accepted theory is the iatrogenic transplantation of endometrial implants to the wound edge during an abdominal or pelvic surgery (1,3,5,6). The diagnosis of scar endometriosis may be challenging. Cyclical changes in the intensity of pain and size of the endometrial implants during menstruation are usually characteristic of classical endometriosis. However, in the largest reported series (7) to date, only 20% of the patients exhibited these symptoms. Patients usually complain of tenderness to palpation and a raised, unsightly hypertrophic scar. Management includes both surgical excision and hormonal suppression (2,8). Oral contraceptives, progestational and androgenic agents have been tried. It is believed that hormonal suppression is only partially effective and surgical excision of the scar is the definitive treatment (8,9). Scar endometriosis is a rare and often elusive diagnosis that can lead to both patient and physician frustration. One should maintain a high level of suspicion in any woman presenting with pain at an incisional site, most commonly following pelvic surgery. A thorough history and physical examination should always be performed, and every surgeon should consider this entity in their differential diagnosis. Acknowledgments The authors had no conflicts of interest to declare and maintained ethical adherence.

References

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