Biomarkers for Diagnosis of Pre-Eclampsia and Endometriosis

Braira Wahid, Rafique S, Shazia Rafique, Ali A, Muhammad Waqar, Amjad Ali, Waqar M, Muhammad Wasim, Ghulam Nabi, Muhammad Idrees, Wasim M, Idrees M
Biomarkers in medicine · 2018 · vol. 12(10) , pp. 1161–1173 · doi:10.2217/bmm-2018-0058 · PMID:30191726 · W2890854722
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This review discusses current biomarkers and omics technologies for early screening of endometriosis and pre-eclampsia, aiming to inform future biomarker development strategies.

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Abstract

Gynecological disorders are leading public health problems in developing countries with substantial impact on women's quality of life. Significant proportion of maternal mortality and reproductive morbidity is attributed to misdiagnosis and mismanagement of pregnancy related lethal pathological conditions and affect women's health. Timely diagnosis is necessary to prevent maternal deaths and to manage complications. Biomarker development will create a wide window of opportunity for early diagnosis. This review discusses the current status of biomarkers and recent advances in 'omics' technology for early screening of endometriosis and pre-eclampsia because of significant global bioburden associated with these disorders. This review will also give baseline data for future biomarker development strategies.

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Condition tags

endometriosis

MeSH descriptors

Biomarkers Endometriosis Pre-Eclampsia Biomarkers Endoglin Endoglin Endometriosis Female Humans Lipocalin-2 Lipocalin-2 Pre-Eclampsia Pregnancy RNA, Untranslated RNA, Untranslated Vascular Endothelial Growth Factor Receptor-1 Vascular Endothelial Growth Factor Receptor-1

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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