Fertility and sterility

OBJECTIVE: To investigate the association of endometriosis with estrogen receptor alpha (ER alpha) and cytochrome P450c17alpha (CYP17) gene polymorphisms in light of the fact that estrogen plays a role in the pathogenesis of endometriosis a…

OBJECTIVE: To evaluate the local matrix metalloproteinase 1 (MMP-1), estrogen receptor (ER) alpha, and ERbeta protein expression in eutopic and dystopic tissue from patients with endometriosis and to compare the endometrial expression patte…

The present study was designed to explore the association between estrogen receptor-alpha gene polymorphism and the risk of endometriosis by investigating the frequency of PvuII, XbaI, and thymine-adenine (TA) repeat polymorphisms in patien…

CCR1 is a CC chemokine receptor with high affinity for RANTES (regulated upon activation, normal T cells expressed and secreted). CCR1 protein and mRNA concentrations in native peritoneal cells were twofold greater, in cultured peritoneal c…

OBJECTIVE: To use tissue microarray in combination with dendrogram cluster analysis to characterize some potential tumorigenic factors in association with tumor size and sex steroid hormone status in uterine leiomyomata. DESIGN: Expression…

OBJECTIVE: To examine fertility, reproductive outcomes, and determinants of fertility after laparoscopic segmental colorectal resection for endometriosis. DESIGN: Retrospective longitudinal study. SETTING: Tertiary university gynecology u…

We report a case of perihepatic adhesion due to severe endometriosis.

OBJECTIVE: To estimate the expression of haptoglobin (Hp) beta chain isoforms in the peritoneal fluid (PF) and plasma (PL) of women with and without endometriosis. DESIGN: Cross-sectional study. SETTING: University hospital. PATIENT(S): …

OBJECTIVE: To confirm the endometrial glandular epithelial and stromal cells in tissue fragments recovered from peritoneal fluid and to quantify haptoglobin expression. DESIGN: Prospective, randomized study. SETTING: University of Missour…

OBJECTIVE: To investigate the macrophage response in endometriosis, we determined expression of human leukocyte antigen (HLA)-ABC, HLA-DR, and their costimulatory molecules by peritoneal fluid (PF) macrophages. DESIGN: Case-control study o…

We describe a 41-year-old woman with disseminated leiomyomatosis peritonei who underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy. Images obtained from laparoscopy and histopathology are presented.

OBJECTIVE: To evaluate the effect of endometriosis and the presence of an ovarian endometrioma on outcomes of conventional in vitro fertilization (IVF). DESIGN: Retrospective study. SETTING: Reproductive Unit, Department of Obstetrics and…

OBJECTIVE: To investigate the possible association between the body burden of dioxin-like compounds and endometriotic disease. DESIGN: Case-control study. SETTING: Gynecology ward in a university hospital. PATIENT(S): Seventy-one women w…

Documentation and communication regarding infertility evaluation and management continue to be a work in progress. Grading systems focused on the degree of infertility and the associated prognosis are a step in the right direction. A subjec…

OBJECTIVE: To examine the toxic effects of tumor necrosis factor alpha (TNF-alpha) on ejaculated spermatozoa and evaluate the ability of infliximab to reverse these effects. DESIGN: Prospective controlled study. SETTING: Cleveland Clinic …

Interleukin (IL)-2 R-627*C homozygote and C allele are related to higher susceptibility to endometriosis. Interleukin-12Rbeta1 codon 378 and IL-18 105 gene polymorphisms are not correlated with endometriosis development.

OBJECTIVE: To evaluate the effectiveness of trichloroacetic acid (TCA) instillation into uterine cavity for the treatment of dysfunctional uterine bleeding (DUB). DESIGN: Prospective clinical study. SETTING: A university research hospital…

OBJECTIVE: To establish a novel endometriosis model that allows for repetitive in vivo analyses of angiogenesis in ectopic endometrial tissue. DESIGN: Intravital fluorescence microscopic study. SETTING: Institute for Clinical and Experime…

Should surgical treatment of presumed endometriosis be advocated for all patients who fail to conceive after multiple IVF cycles? Without appropriately designed clinical studies, there is currently little evidence to support this approach.

OBJECTIVE: To evaluate whether the presence of kissing ovaries at ultrasound is a marker for endometriosis and whether it correlates with the severity of the disease. DESIGN: Prospective observational study. SETTING: Gynecologic departmen…

OBJECTIVE: To report outcomes of laparoscopic management of patients with ovarian remnant (OR). DESIGN: Retrospective chart review. SETTING: Referral practice and tertiary medical center. PATIENT(S): Sixty-four patients with confirmed OR…

OBJECTIVE: To investigate the clinical efficacy and safety of Helica Thermal Coagulator (TC) in the treatment of pelvic pain associated with minimal (stage I) and mild (stage II) endometriosis. DESIGN: A clinical observational study. SETT…

Studies on the respective roles of laparoscopic surgery and IVF in infertile patients with endometriosis and endometriomas are difficult to perform. Appropriate patient management is complex and requires a sophisticated understanding of ind…

OBJECTIVE: To describe the long-term outcome of surgical conservative treatment of bladder endometriosis. DESIGN: Descriptive study. SETTING: Tertiary referral center for the treatment of endometriosis. PATIENT(S): Forty-seven patients w…