Expression and regulation of CCR1 in peritoneal macrophages from women with and without endometriosis

Fritz Wieser, Songül Dogan, Karin Klingel, Klaus Diedrich, Robert N Taylor, Daniela Hornung
Fertility and sterility · 2005 · doi:10.1016/j.fertnstert.2004.12.034 · PMID:15950672
other OA: bronze public-domain-us
🔓 Open OA copy View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

Peritoneal macrophages from women with endometriosis exhibit twofold greater CCR1 protein and mRNA concentrations than those from women without endometriosis.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

CCR1 is a CC chemokine receptor with high affinity for RANTES (regulated upon activation, normal T cells expressed and secreted). CCR1 protein and mRNA concentrations in native peritoneal cells were twofold greater, in cultured peritoneal cells threefold greater, in patients with endometriosis compared to patients without endometriosis, as determined by Western blotting fluorescence activated cell sorting analysis, reverse transcription-polymerase chain reaction, and in situ hybridization.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Endometriosis Macrophages, Peritoneal Receptors, Chemokine Analysis of Variance Cells, Cultured Endometriosis Endometriosis Female Flow Cytometry Gene Expression Regulation Gene Expression Regulation Humans In Situ Hybridization Macrophages, Peritoneal Receptors, CCR1 Receptors, Chemokine Receptors, Chemokine Receptors, Chemokine Reverse Transcriptase Polymerase Chain Reaction Statistics, Nonparametric

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.

Source provenance

europepmc
last seen: 2026-06-13T06:22:48.782012+00:00
pubmed
last seen: 2026-05-13T22:15:35.797702+00:00
unpaywall
last seen: 2026-05-14T19:30:52.867331+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine