Interleukin-2 receptor β (IL-2Rβ)-627*C homozygote but not IL-12Rβ1 codon 378 or IL-18 105 polymorphism is associated with higher susceptibility to endometriosis

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The IL-2Rβ *627*C allele, but not IL-12Rβ1 or IL-18 polymorphisms, was associated with increased susceptibility to endometriosis.

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Abstract

Interleukin (IL)-2 R-627*C homozygote and C allele are related to higher susceptibility to endometriosis. Interleukin-12Rbeta1 codon 378 and IL-18 105 gene polymorphisms are not correlated with endometriosis development.

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Condition tags

endometriosis

MeSH descriptors

Alleles Cytosine Endometriosis Genetic Predisposition to Disease Homozygote Interleukin-18 Receptors, Interleukin Endometriosis Female Humans Interleukin-18 Interleukin-2 Receptor beta Subunit Polymorphism, Genetic Polymorphism, Genetic Receptors, Interleukin Receptors, Interleukin-12

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (16)

Cited by (12)

Source provenance

europepmc
last seen: 2026-07-29T06:27:48.050232+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:15:35.797702+00:00
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