Interleukin-2 receptor beta (IL-2R beta)-627*C homozygote but not IL-12R beta 1 codon 378 or IL-18 105 polymorphism is associated with higher susceptibility to endometriosis
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⤵ 12 in-corpus citations
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The IL-2Rβ *627*C allele, but not IL-12Rβ1 or IL-18 polymorphisms, was associated with increased susceptibility to endometriosis.
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Abstract
Interleukin (IL)-2 R-627*C homozygote and C allele are related to higher susceptibility to endometriosis. Interleukin-12Rbeta1 codon 378 and IL-18 105 gene polymorphisms are not correlated with endometriosis development.
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References (16)
- [Alteration of peritoneal lymphocyte transformation and its interleukin-2 release in patients with infertility and endometriosis] via openalex
- Decreased levels of interleukin-18 in peritoneal fluid but not in serum of patients with endometriosis via openalex
- Decrease in interferon gamma production and impairment of T-lymphocyte proliferation in peritoneal fluid of women with endometriosis via openalex
- Effect of interleukin-8 (IL-8), anti-IL-8, and IL-12 on endometrial cell survival in combined endometrial gland and stromal cell cultures derived from women with and without endometriosis via openalex
- Endometrial ability to implant in ectopic sites can be prevented by interleukin-12 in a murine model of endometriosis via openalex
- Increase in the production of interleukin-6, interleukin-10, and interleukin-12 by lipopolysaccharide-stimulated peritoneal macrophages from women with endometriosis via openalex
- Interleukin-12 and its free p40 subunit regulate immune recognition of endometrial cells: potential role in endometriosis via openalex
- Natural killer activity in stage III and IV endometriosis: impaired cytotoxicity and retained lymphokine responsiveness of natural killer cells via openalex
- Recombinant interleukin-2 corrects in vitro the immunological defect of endometriosis via openalex
- W6715053281 via openalex
- W1990616799 via openalex
- W2028712686 via openalex
- W2091790532 via openalex
- W2117638564 via openalex
- W2325102839 via openalex
- W119129521 via openalex
Cited by (12)
- Identification of Key Differentially Methylated/Expressed Genes and Pathways for Ovarian Endometriosis by Bioinformatics Analysis 2021
- Gestagens in the treatment of endometriosis 2018
- Gestagens in the treatment of endometriosis 2018
- Protein-protein interaction analysis to identify biomarker networks for endometriosis 2017
- Understanding the role of epigenomic, genomic and genetic alterations in the development of endometriosis (review) 2014
- Lymphokine activated killer cells from peripheral blood mononuclear cells of endometriosis of patients improve cytotoxicity to endometriosis cell culture 2011
- Association of interleukin 1beta gene (+3953) polymorphism and severity of endometriosis in Turkish women 2009
- Interleukin-2 receptor beta gene C627T polymorphism in Korean women with endometriosis: a case-control study 2009
- Peritoneal and serum interleukin-18 levels are not increased in women with minimum or mild endometriosis 2009
- Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis 2008
- The effect of intraperitoneal interleukin-2 on surgically induced endometriosis in rats 2007
- Ten estrogen-related polymorphisms and endometriosis: a study of multiple gene-gene interactions 2005
Source provenance
- europepmc
- last seen: 2026-10-16T06:09:50.462052+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:03:18.265172+00:00
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