Fertility and sterility

OBJECTIVE: To investigate c-fos and matrix metalloproteinase-9 (MMP-9) expression in the endometrium from women with or without endometriosis throughout the menstrual cycle, and to explore the correlation of c-fos expression with MMP-9 expr…

OBJECTIVE: To analyze the frequency of peritoneal natural killer (NK) cells expressing the human leukocyte antigen (HLA)-E receptor CD94/NKG2A in patients with endometriosis. DESIGN: Case-control study. SETTING: University hospital. PATI…

Despite the multiple advantages of assisted reproductive technology compared with surgery, there remain several diagnoses for which surgery is still widely performed: distal tubal occlusion, regret of permanent sterilization, and endometrio…

Assisted reproductive technology (ART) and laparoscopy are not mutually exclusive, but coexisting and potentially complimentary treatments. For disease conditions contributing to infertility in addition to other concomitant or potential mor…

OBJECTIVE: To assess long-term fracture risk after hysterectomy, with or without oophorectomy. DESIGN: Population-based, cohort study. SETTING: Olmsted County, Minnesota. PATIENT(S): Women residing in Olmsted County (n = 9,258) who under…

OBJECTIVE: To report a rare complication of GnRH agonist therapy for intestinal endometriosis. DESIGN: Case report. SETTING: University hospital. PATIENT(S): A 45-year-old nulliparous Japanese woman with catamenial digestive symptoms. I…

OBJECTIVE: To report that isolated endometriosis of the sciatic nerve without further manifestation of endometriosis does exist. DESIGN: We describe our technique of laparoscopic neurolysis of the sciatic nerve and the sacral plexus. SETT…

OBJECTIVE: To compare the history of pain complaints of women presenting rectovaginal and rectal endometriosis to show that rectovaginal locations may progress to a rectal involvement of the disease. DESIGN: Retrospective comparative study…

OBJECTIVE: To present a series of six consecutive women with adenomyomas who were successfully managed with a standard treatment strategy to elucidate the feasibility and the effectiveness of laparoscopic treatment of adenomyomas. DESIGN: …

This open-label prospective study evaluated the efficacy of letrozole (2.5 mg/day) combined with norethisterone acetate (2.5 mg/day) in the treatment of pain symptoms related to the presence of rectovaginal endometriosis. The treatment sign…

OBJECTIVE: To assess whether complement components iC3b, C3c, C4, and SC5b-9 may be involved in the pathogenesis of endometriosis. DESIGN: Prospective, experimental trial. SETTING: Medical university. PATIENT(S): 112 women infertile wome…

OBJECTIVE: To analyze the lymph node involvement by endometriotic foci in rectosigmoid endometriosis and to correlate it with clinical and histological parameters including the presence of lymphovascular invasions, which could explain this …

Pelvic pain associated with endometriosis was treated by the long-term administration of a tapering dose of danazol or mid/low doses of oral contraceptives after the end of therapy involving a GnRH agonist (GnRH-a). Results demonstrated tha…

OBJECTIVE: To report a case of clear cell carcinoma in abdominal wall endometriosis after cesarean section. DESIGN: Case report. SETTING: A French oncology center. PATIENT(S): A 38-year-old woman who developed a 10-cm mass in the abdomin…

The expression of mitochondrial genes in granulosa cells was quantitated by real-time polymerase chain reaction. The expression ratio of mitochondrial genes in granulosa cells of patients with severe endometriosis showed no statistically si…

OBJECTIVE: To validate a rat model of endometriosis using complimentary DNA (cDNA) microarrays by identifying common gene expression patterns between experimental and natural disease. DESIGN: Autotransplantation rat model. SETTING: Medica…

OBJECTIVE: To describe a case of monozygotic triplet pregnancy following egg donation and the transfer of a single frozen-thawed embryo. DESIGN: Case report. SETTING: District general hospital and regional department of fetal medicine in …

OBJECTIVE: To non-invasively characterize ectopic uterine tissue (EUT) development in a modified autologous rat surgical model of endometriosis using magnetic resonance imaging (MRI). DESIGN: Investigational MRI study. SETTING: A pharmace…

In this experimental study on endometriosis, the majority of the implants were successfully detected with technetium-(99mTc) labeled red blood cell scintigraphy.

Recurrent chronic pelvic pain should prompt physicians to reassess the patient. The threshold to perform laparoscopy, and to consider and surgically treat all potential disease associated with pain, even non-gynecologic etiologies, should b…

OBJECTIVE: To investigate the anti-inflammatory effect of n-3 eicosapentaenoic acid (EPA) compared with n-6 linoleic acid (LA) in an endometriosis rat model. We focused on the relationship between lipid metabolism and inflammatory reactions…

OBJECTIVE: To assess whether a correlation exists between angiogenesis in ovarian endometrioma with the presence of pelvic pain. DESIGN: Prospective study. SETTING: Tertiary-care university hospital. PATIENT(S): Sixty-five patients (mean…

OBJECTIVE: To report on a patient with endomyometrioma with atypias and to review the literature. DESIGN: Case report and literature review. SETTING: Clinical and pathologic. PATIENT(S): A 33-year-old nulliparous woman with right flank p…

OBJECTIVE: To review outcomes and pathologic findings of a primarily minimally invasive approach to ovarian remnant syndrome. DESIGN: Data were abstracted from medical records documenting bilateral salpingo-oophorectomy and subsequent trea…